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Background
Testicular germ cell tumors (TGCTs) are highly sensitive to platinum‐based chemotherapy, and wild‐type p53 seems to play a pivotal role in this susceptibility. On the other hand, overexpression of MDM2 seems to entail treatment resistance and unfavorable prognosis.
Objectives
We aimed to describe p53 and MDM2 immunoexpression in a well‐characterized cohort of primary and metastatic TGCTs...
Background Covalent RNA modifications, such as N-6-methyladenosine (m6A), have been associated with various biological processes, but their role in cancer remains largely unexplored. m6A dynamics depends on specific enzymes whose deregulation may also impact in tumorigenesis. Herein, we assessed the differential abundance of m6A, its writer VIRMA and its reader YTHDF3, in testicular germ cell tumors...
This paper presents a recommendation system based on sentiment analysis of sentences extracted from Social Networks considering an algorithm which depends on the adverb found in the sentence. Furthermore, the recommendation system has a low complexity, therefore the perceived impacts on the analysis of energy consumption on electronic devices is almost negligible.
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