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In magnetomotive (MM) ultrasound (US) imaging, magnetic nanoparticle (MNP) labeled tissue is moved by a magnetically induced force. Therefore, all MNPs in the field of view are excited simultaneously and a high field strength results in magnetic saturation of MNPs, hence, in a linear response. The linear displacements are spatially resolved by US tracking methods. Recently [1], it was proposed to...
In magnetomotive ultrasound imaging, magnetic nanoparticle labeled tissue is moved by a magnetically induced force. This force is commonly modeled as linear with respect to the applied magnetic field strength. However, it is known that iron oxide nanoparticle suspensions exhibit a superparamagnetic, i.e., nonlinear, magnetization characteristic. In this contribution, a magnetic field configuration...
In Magnetomotive Ultrasound (MMUS), tissue embedded magnetic nanoparticles (MNP) are mechanically excited by a magnetic field. Relatively small forces on the MNP result in small tissue displacements and a low SNR, when US-based displacement tracking is performed. From the application of elastography techniques it is known that the axial displacement of soft tissues shows a resonant behavior depending...
In Magnetomotive Ultrasound (MMUS), tissue embedded magnetic nanoparticles (NP) are mechanically excited by a magnetic field and the resulting motion of the surrounding tissue is tracked to image the NP distribution. This mechanism of excitation is of particular interest for elastography applications and offers an alternative to the acoustic radiation force excitation in order to estimate the tissue's...
Magnetic particle imaging (MPI) is a novel tomographic modality that allows real-time imaging of the biodistribution of magnetic nanoparticles with high sensitivity and spatial resolution. In addition, real-time temperature monitoring using the same particles was demonstrated. High intensity focused ultrasound (HIFU) therapy to date relies on magnetic resonance imaging (MRI) as the clinical monitoring...
Characterization of viscoelastic properties of phantom materials has been an important subject to validate methods for ultrasound elastography. The frequency response of the motion of a rigid sphere, embedded in a viscoelastic medium, that is excited by an acoustic radiation force (ARF), has been utilized to estimate the viscoelastic properties of the medium. This response is commonly tracked with...
In linear system identification, the coexistence of parameter-misadjustment and output-error metrics has turned out very practical and their relation is well understood. In nonlinear system identification, however, such tools for performance evaluation are far less developed and each nonlinear type may need its own treatment. This paper focuses on the Hammerstein model as an instance of nonlinear...
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