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We present a microrobotic platform that combines MEMS-based capacitive force sensing technology, a dual-stage positioning system and a real-time control and acquisition architecture with computer vision automation to manipulate and mechanically characterize growing plant cells. The topography accuracy of the system, using a silicon wafer sample is measured to be 28 nm(1σ, 200Hz). With an SI-traceable...
Understanding the process of cellular morphogenesis requires the characterization of local mechanical properties of living cells in situ. For this purpose, an automated microrobotic system, the Cellular Force Microscope (CFM) has been developed. Its suitability for single cell characterization has been reported in previous work and extensive use on characterization of both single cells and tissues...
As the field of biology becomes a more quantitative and predictive natural science, an increasing need for investigation and quantification of the mechanics of growth at individual cellular levels arises. This paper describes a microrobotic force-feedback based system and its application to the mechanical characterization of living, growing plant cells. The Cellular Force Microscope (CFM) is capable...
As the field of biology becomes a more quantitative and predictive natural science, an increasing need for investigation and quantification of the mechanics of growth at individual cellular levels arises. This paper describes a microrobotic force-feedback based system and its application to the mechanical characterization of living, growing plant cells. The Cellular Force Microscope (CFM) is capable...
The monolithically integrated two-axis microtensile/compression tester and its application to the stiffness measurement of individual plant cells are presented. It consists of a two-axis electrostatic actuator with capacitive position feedback and a two-axis capacitive micro-force sensor. The actuation range is +/-16 μm along both axes with a spatial resolution of 20 nm. The force sensing...
We present a novel polymer based wafer level fabrication process for micro thermoelectric generators (μTEGs) for the application on non-planar surfaces. The generators are fabricated by subsequent electrochemical deposition (ECD) of Cu and Ni in a 190-μm thick flexible polymer mold formed by photolithographic (PL) patterning of SU-8. First generators were tested and characterized. The TEG generated...
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