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High potassium (K + ) intake reduces blood pressure in populations at high risk for hypertension and protects myocardium from injury. We examined the basis of vaso-protective effect of dietary on cardiovascular function. New Zealand white rabbits were fed diet containing normal amount of K + or low K + diet for 7 days (n = 7, each group). Carotid arteries and hearts were...
Low density lipoproteins (ox-LDL) are atherogenic and high levels of ox-LDL are associated with large infarcts following coronary artery occlusion and reperfusion. Other studies show that cardiomyocytes undergo apoptosis upon ischemia-reperfusion, perhaps a result of free radical release. We have recently found that anoxia-reoxygenation results in about 20-30% apoptosis in cultured human coronary...
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