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Objective
To review the current status of germline and somatic (tumour) genetic testing for prostate cancer (PCa), and its relevance for clinical practice.
Methods
A narrative synthesis of various molecular profiles related to their clinical context was carried out. Current guidelines for genetic testing and its feasibility in clinical practice were analysed. We report the main identified genetic...
Study Type – Therapy (cohort)Level of Evidence 2bWhat's known on the subject? and What does the study add?Very little is known about the safety and potential oncological benefit of performing a retroperitoneal lymph node dissection at time of nephroureterectomy for upper tract tumours.This study is the first clinical trial to prospectively validate the safety and feasibility of a retroperitoneal lymph...
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