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Objectives
This study aims to optimize the human extended pluripotent stem cell (EPSC) to trophectoderm (TE)‐like cell induction with addition of EGF and improve the quality of the reconstructing blastoids.
Materials and Methods
TE‐like cells were differentiated from human EPSCs. RNA‐seq data analysis was performed to compare with TE‐like cells from multiple human pluripotent stem cells (hPSCs)...
Objective
Premature ovarian insufficiency (POI) is a refractory disease that seriously affects female fertility. Growing body of evidence has indicated mesenchymal stem cells (MSCs) as promising resources in regenerative medicine. In this study, we treated POI patients with umbilical cord‐derived MSCs (UCMSCs) and then investigated the restoration of ovarian function and clinical outcomes through...
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