Search results for: F. Wolf

Items from 1 to 20 out of 227 results

article

Development of a novel low‐background noise blood loop model for testing blood‐contacting biomaterials and medical devices in fresh human blood

Patrick Cahalan, Michael Hegy, Linda Cahalan, Ben Curry, more

Journal of Biomedical Materials Research Part B: Applied Biomaterials > 111 > 1 > 38 - 50

A novel low volume blood loop model (Ension Triad System [ETS]) incorporating pulsatile flow and a proprietary low‐activation blood‐contacting surface (Ension bioactive surface [EBS]) enabling high signal‐to‐noise performance is described. The ETS system incorporates a test chamber that allows direct comparison of material samples or finished medical devices such as catheters with varying compositions...

article

Evaluating habitat selection models to predict critical habitat for mountain goats in northwest British Columbia

Jesse F. Wolf, Kara M. MacAulay, Krystal D. Kriss

The Journal of Wildlife Management > 86 > 5 > n/a - n/a

Anthropogenic activity imposes increasing pressure on wildlife populations globally; these pressures can affect habitat suitability and function, modify wildlife space use, and influence population viability. Native mountain goat (Oreamnos americanus) populations can be negatively affected by anthropogenic disturbance and modify their space use in response to land development and recreational activity...

article

In vitro methodology for medical device material thrombogenicity assessments: A use condition and bioanalytical proof‐of‐concept approach

Michael F. Wolf, Gaurav Girdhar, Arielle A. Anderson, Samantha R. Ubl, more

Journal of Biomedical Materials Research Part B: Applied Biomaterials > 109 > 3 > 358 - 376

Device manufacturers and regulatory agencies currently utilize expensive and often inconclusive in vivo vascular implant models to assess implant material thrombogenicity. We report an in vitro thrombogenicity assessment methodology where test materials (polyethylene, Elasthane™ 80A polyurethane, Pebax®), alongside positive (borosilicate glass) and negative (no material) controls, were exposed to...

article

Process design and development of a mammalian cell perfusion culture in shake‐tube and benchtop bioreactors

Moritz K. F. Wolf, Andrea Müller, Jonathan Souquet, Hervé Broly, more

Biotechnology and Bioengineering > 116 > 8 > 1973 - 1985

The development of mammalian cell perfusion cultures is still laborious and complex to perform due to the limited availability of scale‐down models and limited knowledge of time‐ and cost‐effective procedures. The maximum achievable viable cell density (VCD_max), minimum cell‐specific perfusion rate (CSPR_min), cellular growth characteristics, and resulting bleed rate at steady‐state operation are key...

article

Clinimetric evaluation and clinical outcomes of the Dutch version of the Chronic Ear Survey

S. Geerse, R. J. Haan, M. J. F. Wolf, F. A. Ebbens, more

Health and Quality of Life Outcomes > 2019 > 17 > 1 > 1-7

Background To validate and evaluate the reliability of the Dutch version of the Chronic Ear Survey (CES) in patients suffering from Chronic Suppurative Otitis Media (CSOM) and to evaluate clinical outcomes of surgery using this questionnaire. Methods We developed the Dutch version of the CES (D-CES) using forward-backward translation of the original CES into the Dutch language. Next, patients with...

article

Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition

Moritz K. F Wolf, Aurélie Closet, Monika Bzowska, Jean‐Marc Bielser, more

Biotechnology Journal > 14 > 2 > n/a - n/a

Mammalian cell perfusion cultures represent a promising alternative to the current fed‐batch technology for the production of various biopharmaceuticals. Long‐term operation at a fixed viable cell density (VCD) requires a viable culture and a constant removal of excessive cells. Product loss in the cell removing bleed stream deteriorates the process yield. In this study, the authors investigate the...

article

Redox-influenced trace element compositional differences among variably aqueously altered CM chondrites

Jon M. Friedrich, Neyda M. Abreu, Stephen F. Wolf, Julianne M. Troiano, more

Geochimica et Cosmochimica Acta > 2018 > 237 > C > 1-17

It is generally agreed that the CM chondrites are remarkably compositionally uniform. To date, this observation has largely been based on major and selected trace element bulk elemental abundances. Here, we examine the trace element compositional uniformity of the CM chondrites in detail. We quantified the abundances of 43 trace elements in 21 CM chondrites displaying variable degrees of petrographically...

article

Sm‐p80‐based schistosomiasis vaccine: double‐blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission‐blocking efficacy

Weidong Zhang, Adebayo J. Molehin, Juan U. Rojo, Justin Sudduth, more

Annals of the New York Academy of Sciences > 1425 > 1 > 38 - 51

Schistosomiasis is of public health importance to an estimated one billion people in 79 countries. A vaccine is urgently needed. Here, we report the results of four independent, double‐blind studies of an Sm‐p80‐based vaccine in baboons. The vaccine exhibited potent prophylactic efficacy against transmission of Schistosoma mansoni infection and was associated with significantly less egg‐induced pathology,...

article

PB15. Neurophysiological biomarker for the clinical development of tuberous sclerosis

F. Wolf, N. Japaridze, M. Muthuraman, G. Wiegand, more

Clinical Neurophysiology > 2018 > 129 > 8 > e61

To investigate the neuronal networks in children with tuberous sclerosis complex (TS) undergoing treatment with Everolimus.Sleep and wake electroencephalography (EEG) before and one year after the start of the treatment with Everolimus were investigated in 13 patients with TS. To investigate functional and effective connectivity within the network generating the delta and theta activity in the background...

article

UAV route planning for active disease classification

Kelen C. T. Vivaldini, Thiago H. Martinelli, Vitor C. Guizilini, Jefferson R. Souza, more

Autonomous Robots > 2019 > 43 > 5 > 1137-1153

Eucalyptus represents one of the main sources of raw material in Brazil, and each year substantial losses estimated at $400 million occur due to diseases. The active monitoring of eucalyptus crops can help getting accurate information about contaminated areas, in order to improve response time. Unmanned aerial vehicles (UAVs) provide low-cost data acquisition and fast scanning of large areas, however...

article

Cover Image

P. Hoffmann, S. Flege, W. Ensinger, F. Wolf, more

X‐Ray Spectrometry > 47 > 3 > i - i

The cover image, by Peter Hoffmann et al., is based on the Research Article MA‐XRF investigation of the Altenberg Retable from 1330, DOI: 10.1002/xrs.2829. Photo credit: Städel Museum, Frankfurt am Main / 3D‐reconstruction: Yannic Jäckel

article

MA‐XRF investigation of the Altenberg Retable from 1330

P. Hoffmann, S. Flege, W. Ensinger, F. Wolf, more

X‐Ray Spectrometry > 47 > 3 > 215 - 222

The Altenberg Retable is one of the most important works of German art from the early 14th century. Composed of a shrine, a Madonna figure, and painted wings, it once adorned the high altar of the convent church in Altenberg/Lahn. The side and rear walls of the shrine were overpainted in 1609. Although conventional methods such as infrared reflectography and X‐ray radiography could not reveal the...

article

Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation

Vadim A. Ivanov, Roman F. Wolf, James F. Papin, Michael P. Anderson, more

Journal of Medical Primatology > 47 > 1 > 46 - 50

Background In various types of pulmonary research, pulmonary function testing (PFT) is performed to quantify the severity of lung disease. Induction of apnea and positive pressure ventilation are required for accurate PFT measurements in non‐cooperative subjects. We compared two methods of apnea induction in infant olive baboons (Papio anubis). Methods Pulmonary function testing results were compared...

article

Längen‑, Achs- und Torsionskorrekturen mit Distraktionsmarknägeln

P. H. Thaller, N. Degen, J. Fürmetz, F. Wolf

Trauma und Berufskrankheit > 2017 > 19 > 4 > 182-190

Hintergrund Kallusdistraktion mittels vollimplantierbarer Distraktionsmarknägel ist ein etabliertes Verfahren zur Extremitätenverlängerung. Ein knappes Dutzend verschiedener Systeme ist bekannt. Distraktionsmarknägel unterscheiden sich v. a. im Antriebsmechanismus und in Hub, Dimensionen und Materialien. Fragestellung Aus einer Analyse von Erfahrungen mit 5 verschiedenen Distraktionsmarknägeln lassen...

article

Safe Optimization of Highway Traffic With Robust Model Predictive Control-Based Cooperative Adaptive Cruise Control

Carlos Massera Filho, Marco H. Terra, Denis F. Wolf

IEEE Transactions on Intelligent Transportation Systems > 2017 > 18 > 11 > 3193 - 3203

Road traffic crashes have been the leading cause of death among young people. Most of these accidents occur when the driver becomes distracted due to fatigue or external factors. Vehicle platooning systems, as cooperative adaptive cruise control, are one of the results of efforts devoted to the development of technologies for decreasing the number of road crashes and fatalities. Previous studies have...

article

Reply to “Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease; Methodologic Issues,” by Safiri, Saeid et al.

Zeljka Jutric, Yelena Rozenfeld, Jan Grendar, Ronald F. Wolf

Annals of Surgical Oncology > 2017 > 24 > 3 > 667-668

article

Management of labyrinthine fistula: hearing preservation versus prevention of residual disease

S. Geerse, M. J. F. Wolf, F. A. Ebbens, E. Spronsen

European Archives of Oto-Rhino-Laryngology > 2017 > 274 > 10 > 3605-3612

The objective of the study was to evaluate postoperative hearing and disease control after cholesteatoma surgery for labyrinthine fistulas. In a retrospective cohort study, we evaluated a consecutive cohort comprising 44 patients (45 ears) with labyrinthine fistulas associated with chronic otitis media with cholesteatoma who underwent surgery between 2002 and 2015. We looked at patient characteristics,...

article

I3DC : mise en place d’un cours intensif européen de maladies infectieuses

C. Charlier, I. Johannessen, C. Mackintosh, D. Wilks, more

M�decine et Maladies Infectieuses > 2017 > 47 > 4(S) > S34

L’enseignement facultaire des maladies infectieuses est confronté à des défis qui bouleversent notre pédagogie : la désaffection par les étudiants des enseignements classiques conduit à développer des approches plaçant l’étudiant dans un rôle d’apprentissage actif ; la prise en compte de la dimension transversale et internationale « one health » de la discipline nécessite une coopération entre enseignants...

chapter

Guaranteed cost approach for robust model predictive control of uncertain linear systems

Carlos M. Massera, Marco H. Terra, Denis F. Wolf

2017 American Control Conference (ACC) > 4135 - 4140

2017 American Control Conference (ACC)

In this paper we propose a constrained guaranteed cost robust model predictive controller (GCMPC) for uncertain discrete time systems. This controller was developed based on a quadratic cost functional and guarantee robustness with respect to quadratically bound uncertainties. Such a class of problems is currently intractable by Min-Max Robust Model Predictive Controllers without polytopic approximations...

article

SP-0493: The role of spacers in the era of highly conformal, hypo-fractionated, image guided, adaptive radiotherapy of the prostate

P. Scherer, F. Wolf, C. Gaisberger, F. Sedlmayer

Radiotherapy and Oncology > 2017 > 123 > S1 > S262-S263

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INFONA - science communication portal

Search results for: F. Wolf

Development of a novel low‐background noise blood loop model for testing blood‐contacting biomaterials and medical devices in fresh human blood

Evaluating habitat selection models to predict critical habitat for mountain goats in northwest British Columbia

In vitro methodology for medical device material thrombogenicity assessments: A use condition and bioanalytical proof‐of‐concept approach

Process design and development of a mammalian cell perfusion culture in shake‐tube and benchtop bioreactors

Clinimetric evaluation and clinical outcomes of the Dutch version of the Chronic Ear Survey

Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition

Redox-influenced trace element compositional differences among variably aqueously altered CM chondrites

Sm‐p80‐based schistosomiasis vaccine: double‐blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission‐blocking efficacy

PB15. Neurophysiological biomarker for the clinical development of tuberous sclerosis

UAV route planning for active disease classification

Cover Image

MA‐XRF investigation of the Altenberg Retable from 1330

Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation

Längen‑, Achs- und Torsionskorrekturen mit Distraktionsmarknägeln

Safe Optimization of Highway Traffic With Robust Model Predictive Control-Based Cooperative Adaptive Cruise Control

Reply to “Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease; Methodologic Issues,” by Safiri, Saeid et al.

Management of labyrinthine fistula: hearing preservation versus prevention of residual disease

I3DC : mise en place d’un cours intensif européen de maladies infectieuses

Guaranteed cost approach for robust model predictive control of uncertain linear systems

SP-0493: The role of spacers in the era of highly conformal, hypo-fractionated, image guided, adaptive radiotherapy of the prostate

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