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Abstract. Nerve fibre pathology is poorly described in diabetic patients with mild neuropathy and has not been adequately related to clinical evaluation, quantitative sensory examination and neurophysiology. Sural nerve myelinated and unmyelinated fibre pathology was morphometrically quantified and related to the presence of pain and conventional measures of neuropathic severity in 15 diabetic patients...
Abstract Structural abnormalities of the perineurium from six spontaneously diabetic dogs (diabetes duration 48 years and six control animals were quantified using detailed electron microscopic morphometric methods on superficial peroneal nerve biopsy specimens. Total perineurial sheath thickness (m) was significantly increased in diabetic (8.8 0.6) compared to control animals (6.2 0.3) (P 0.02)....
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