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A 28-day oral gavage toxicity study in the rat with 17α-methyltestosterone was conducted as part of the international validation exercise on the modified Enhanced OECD Test Guideline 407 (Organisation for Economic Co-operation and Development, Paris). Special emphasis was placed on the endocrine mediated effects exerted by 17α-methyltestosterone, a potent androgen agonist. The test compound was administered...
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