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Peptides derived from a conserved region of the heavy chain of HLA-B2702 (a.a. 75-84)(Allotrap(R) 2702) have been shown to be immunomodulatory, resulting in graft prolongation in mouse Allotransplantation. We are evaluating the effect of the peptide on pig to mouse islet Xenotransplantation (Xeno-Tx).Adult pigs' pancreases were distended with .9mg/ml collagenase. Islets were isolated using an automated...
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