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Quantitative ultrasound is a promising and relative recent method for the assessment of bone. In this work, the interaction of ultrasound with the porosity of cortical bone is investigated for different frequencies. Emphasis is given on the study of complex scattering effects induced by the propagation of an ultrasonic wave in osseous tissues. Numerical models of cortical bone are established with...
Competent fracture healing monitoring and treatment requires an extensive knowledge of bone biology and microstructure. The use of non-invasive and non-radiating means for the monitoring of the bone healing process has gained significant interest in recent years. Ultrasound is considered as a modality which can contribute to the assessment of bone status during the healing process, as well as, enhance...
The bone healing process involves a sequence of cellular action and interaction, regulated by biochemical and mechanical signals. Experimental studies have shown that ultrasound accelerates bone solidification and enhances the underlying healing mechanisms. An integrated computational model is presented for deriving predictions of bone healing under the presence of ultrasound.
Cortical bone is a heterogeneous, composite medium with a porosity from 5–10%. The characterization of cortical bone using ultrasonic techniques is a complicated procedure especially in numerical studies as several assumptions must be made to describe the concentration and size of pores. This study presents numerical simulations of ultrasound propagation in two-dimensional numerical models of cortical...
The role of quantitative ultrasound as a diagnostic and monitoring tool in bone pathologies has been widely investigated both experimentally and numerically. Recently, the numerical studies have focused on the exploitation of high-resolution imaging data of bone's microarchitecture in order to develop more realistic computational models of osteoporotic bones. In this work, we present numerical simulations...
Bone is a medium with a complex microstructure, consisting of a nonhomogeneous and anisotropic porous network. The numerical study of the ultrasound scattering by cancellous and cortical bone has attracted the interest of several research groups worldwide. In this work, we employed the boundary element method to perform numerical simulations of ultrasonic wave propagation in two-dimensional computational...
Bone healing involves a series of complicated cellular and molecular mechanisms that result in bone formation. Several mechanobiological models have been developed to simulate these cellular mechanisms via diffusive processes. In most cases solution to diffusion equations is accomplished using the Finite Element Method (FEM) which however requires global remeshing in problems with moving or new born...
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