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Views about the importance of the role of molluscicides in the integrated control of human schistosomiasis have passed through cyclical changes over the past 15 years. For a time, it was hoped that chemotherapy alone would achieve significant morbidity control; it has since become clear that molluscicides cannot be easily excluded from the anti-schistosome armoury. In this review, Sheena Perrett...
The West African legume Millettia thonningii is used in Ghana as an anthelmintic and as a purgative agent. A chloroform extract of the seeds of Millettia thonningii which is known to be molluscicidal and cercaricidal was topically applied to mouse skin 2 and 24 h prior to exposure to Schistosoma mansoni cercariae. The presence of Millettia thonningii extract components on the surface of the skin...
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