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Analgesic therapy is based on the sequential treatment of pain, in which opioids are drugs of last resource and known to be highly effective, but are also responsible for undesirable side effects, tolerance and addiction. There is a need for new drugs with alternative targets in order to minimize side effects and improve treatment efficacy. Mastoparans are an abundant class of peptides in wasp venom...
The purpose of this study was to compare the flexural fatigue and torsional resistance of ProFile GT and GT Series X instruments, taking into account their structural and dimensional characteristics.Instrument diameter at each millimeter from the tip and pitch length were the dimensional parameters measured. Chemical composition was determined by energy-dispersive x-ray spectroscopy and phase constitution...
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