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The effect of priming and boosting with pspA/EF5668 and purified recombinant PspA/EF5668 was examined. With this strategy CBA/N mice were protected against fatal challenge with Streptococcus pneumoniae EF5668. Anti-PspA antibody titers were elevated, and Western analysis with the immune serum demonstrated cross-reactivity with PspA from several different pneumococcal isolates, representing different...
Ischemic complications after total knee arthroplasty (TKA) are rare. There is a reported association with chronic lower extremity ischemia (CLEI), however. This prospective study examined changes in blood pressure in the lower limb during the early postoperative period. Arterial blood pressure was assessed before and after TKA by the ankle brachial pressure index (ABPI) using Doppler ultrasonography...
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