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Gd3+‐aggregated gold nanoclusters (AuNCs) encapsulated by silica shell (Gd3+‐A‐AuNCs@SiO2 NPs) were strategically designed and prepared. The as‐prepared nanoparticles exhibit aggregation‐enhanced fluorescence (AEF), with an intensity that is up to 3.8 times that of discrete AuNCs. The clusters served as novel nanoprobes for in vitro and in vivo multimodal (fluorescence, magnetic resonance, and computed...
A new type of drug-delivery system (DDS) was constructed, in which the anti-cancer drug doxorubicin (DOX) was conjugated to the ultra-small sized (sub-10 nm) BaGdF 5 :Yb 3+ /Tm 3+ based upconversion nanoparticles (UCNPs). This multifunctional DDS simultaneously possesses drug delivery and optical/magnetic/X-ray computed tomography imaging capabilities. The DOX can be selectively...
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