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Hepatitis B virus (HBV) infection is a major public health problem, and HBV-related acute-on-chronic liver failure (HBV-ACLF) has an extremely poor prognosis due to a lack of understanding of pathogenesis as well as a lack of effective treatments. Signals from the inhibitory receptor programmed death-1 (PD-1) have been demonstrated to be involved in regulating the pathogenesis of infectious diseases...
Hepatitis B virus (HBV) is a major public health problem, and HBV‐related acute‐on‐chronic liver failure (HBV‐ACLF) has an extremely poor prognosis due to a lack of effective treatments. B7‐H3 and B7‐H4 are two novel members of the B7 superfamily that are actively involved in regulating the pathogenesis of infectious diseases. However, the intrahepatic expression of both members in HBV‐ACLF patients...
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