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BACKGROUNDThe purpose of this study was to evaluate predictors of early distant brain failure (DBF) and salvage whole‐brain radiotherapy (WBRT) after treatment with stereotactic radiosurgery (SRS) for brain metastases and create a clinically relevant risk score to stratify patients’ risk for these events.
METHODSThe records of 270 patients with brain metastases who were treated with SRS between 2003...
BACKGROUNDThe patterns of lobar involvement, optimal treatment, and disease course among patients with gliomatosis cerebri (GC) have not been fully characterized. The current study evaluates the clinical presentations and outcomes for patients with GC treated with radiation therapy (RT) at our institution.
METHODSA total of 26 patients (25 with follow‐up) with GC were diagnosed and treated between...
BACKGROUNDLymph node extracapsular extension (ECE) is a known adverse prognostic factor in head and neck cancer and is an indication for adjuvant chemoradiation (CRT). However, the extent of ECE may provide additional prognostic information in the setting of adjuvant CRT.
METHODSThis study included 350 patients with oral cavity cancer (72.6%) or bulky/nonfunctional laryngeal cancer (27.4%) who underwent...
BACKGROUNDC‐reactive protein (CRP) has been associated with outcomes in patients with metastatic adenocarcinoma of the prostate. Associations between prostate adenocarcinoma‐specific endpoints and CRP in patients who are treated for localized disease remain unknown.
METHODSIn total, 206 patients who received radiation therapy for adenocarcinoma of the prostate had at least 1 CRP measured in follow‐up...
BACKGROUNDAdjuvant radiotherapy (A‐RT) for patients with resected pancreatic adenocarcinoma (PAC) is controversial. In the current study, the authors aim to determine whether there is an association between overall survival (OS) and A‐RT dose.
METHODSNational Cancer Data Base (NCDB) data were obtained for all patients who received A‐RT for resected PAC from 1998 through 2002. Univariate and multivariate...
BACKGROUND:Recent studies have demonstrated the feasibility of combining oxaliplatin with 5‐fluorouracil (5‐FU) or capecitibine and radiation therapy. The addition of bevacizumab to chemotherapy improves overall survival for metastatic disease. We initiated a phase 2 trial to evaluate preoperative capecitabine, oxaliplatin, and bevacizumab with radiation therapy followed by surgery and postoperative...
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