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Parkinsons disease (PD) involves several genetic and environmental components. Heat-shock protein70, a chaperone that is up-regulated in stress responses and that refolds protein, may be involved in the pathogenesis of PD. We have investigated the association of polymorphisms 110 A/C, +190 G/C, +1267 A/G, +2074 G/C, and +2437 G/C in the 5 and coding regions of the HSP70-1, HSP70-2, and HSP70-hom genes...
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