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Objective
To investigate the role of the inflammatory lipid mediator leukotriene B4 (LTB4) and its receptor, BLT1, in the development and progression of systemic sclerosis (SSc).
Methods
Serum levels of LTB4 were compared in 64 patients with SSc and 80 healthy controls. Skin and lung tissue sections from patients with SSc and healthy donors were immunostained for leukotriene A4 hydrolase (LTA4H),...
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