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AimWe wished to determine the effect of continuous β‐receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect.
MethodsAlveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β‐agonist isoproterenol (200 μg kg−1h−1 sc) or vehicle. Alveolar fluid clearance in artificially ventilated rats was determined over 1 h by infusion...
Aim: Congestive heart failure (CHF) is associated with increased renal sympathetic nerve activity and renal sodium retention. Rats with CHF display increased expression of the Na–K–2Cl cotransporter (NKCC2) in the renal medullary thick ascending limb of the loop of Henle (mTAL), and arginine vasopressin (AVP)‐stimulated cAMP formation in mTAL segments is increased in rats with CHF. The aim of the...
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