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In the pathogenesis of central nervous system (CNS) disorders, an increasingly important role is attributed recently to unhealthy lifestyle, which consists primarily of a high caloric diet (i.e., western), chronic exposure to stress, and lack of physical activity. However, the mechanisms responsible for energy metabolism impairment induced by unhealthy lifestyles compromising CNS functions are poorly...
INTRODUCTION: The ketogenic diet (KD) is high fat and low carbohydrate diet type. Ketogenic metabolism is characterized by moderate hypoglycemia. It also leads to the use of ketone bodies as an alternative source of energy for the organism. In the last decade, the influence of various factors on the gut microbiota has been noticed. The gut microbiota includes bacteria as well as fungi, archaea, viruses,...
INTRODUCTION: Autophagy is a cellular recycling mechanism essential for maintenance of cell homeostasis and viability, especially during stress conditions; hence, autophagy is involved in a number of physiological and pathological processes. Autophagy is thought to be involved in anti‑aging and neuroprotective effects of caloric restriction, Sirtuin 1 activation, inhibition of insulin/ insulin-like...
INTRODUCTION: The ketogenic diet (KD) is used to manage drug‑resistant epilepsy in children. The KD directs the metabolism towards fat consumption as an alternative source of caloric demand, thus a state similar to starvation is created. The gut‑brain axis is associated with biochemical signaling between the large intestine and the nervous system via gut microbiota. It seems that, for an efficient...
INTRODUCTION: In the recent years, more attention is attributed to the impact of diet on central nervous system function. An increasing number of diseases, including neurological disorders, results from inadequate dietary habits. Diet, however, can affect the function of brain and mental processes in a negative as well as a beneficial way. The diet with well‑documented neuroprotective effects is a...
INTRODUCTION: High fat diets are characterized by a high fat content with an adequate proportion of proteins and carbohydrates. For a long time, the ketogenic diet has been used in the treatment of epilepsy; however, its neuroprotective properties indicate its putative and broader application in the treatment of neurodegenerative diseases and neurodevelopmental disorders. AIM(S): The present study...
Background: The increasing problem of overweight and obesity in children is the reason for taking further actions leading to mass reduction, because, in contrast to adults, the consequences of this pathology in young people are still not well known. The intervention actions that can lead to reduction in mass are not easy to find in literature, and their long-term effects are unknown. The aim of this...
One of the most dangerous pollutants in the atmosphere is particulate matter (PM), which can be suspended in the air for weeks and has a negative impact on human health when inhaled. The most effective method for clearing the air of PM is through phytoremediation, whereby plants act as biological filters. PM also has a negative impact on plants, but knowledge of the effects of PM on the photosynthetic...
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