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The responsible (rational, prudent) use of antibiotics in veterinary medicine is an issue that is widely discussed and debated recently. The discussion takes place at various levels, including in the parliament of the European Union (EU). A detailed knowledge of pharmacology, in particular in the field of pharmacokinetics and pharmacodynamics of antimicrobial agents, is essential for the prudent use...
The aim of the study was to develop an analytical method adequate to determine the tiamulin in plasma after administration in therapeutic values, calculation of the pharmacokinetic parameters of tiamulin in broiler chickens and the evaluation of the bioequivalence of two veterinary formulations. In order to determine the tiamulin in investigated material the HPLC technique with UV-VIS detection was...
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