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The aim of the study was to analyze the frequency and location of tumors in domestic as well as exotic animals in Lower Silesia. The research material consisted of 4174 cases of malignancies from dogs, cats, horses and exotic animals taken at the time of surgery or biopsy sections. The largest group consisted of tumors of dogs – 3519 cases (84.31%), followed by cat – 498 cases (11.93%), ferrets –...
The aim of the study was to assess the microvessel density based on the analysis of the expression of the CD31, VEGF, and LIMS-1 proteins in canine mast cell tumours. The study was conducted on 60 mastocytomas; 16 cases were classified as the grade I, 26 as the grade II, and 18 as the grade III. Statistical analysis showed a positive correlation only between the grade of the tumour and the expression...
Immunohistochemical profiles of the most common canine testicular tumours, including the Leydig cell tumours, seminomas, and Sertoli cell tumours were analysed, and the results were compared with those obtained in the corresponding txpes of human testicular neoplasms. The expressions of vimentin, von Willebrand factor (FVIII), chromogranin A, synaptophysin, and MCM3 were quantified. In the case of...
The aim of the study was to demonstrate and evaluate the expression of N-cadherin and survivin in spontaneous osteosarcoma tumours in dogs compared to the expression of these proteins in an established (D-17) cell line of canine osteosarcoma. Osteosarcoma samples were taken from the limbs of 15 dogs and fixed in 7% buffered formalin. An adherent canine osteosarcoma cell line (D-17) was also used for...
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