Search results for: V. Nazarov

Items from 1 to 20 out of 179 results

article

Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice

Aurélie Poli, Anaïs Oudin, Arnaud Muller, Ilaria Salvato, more

Allergy > 78 > 3 > 682 - 696

Background Numerous patient‐based studies have highlighted the protective role of immunoglobulin E‐mediated allergic diseases on glioblastoma (GBM) susceptibility and prognosis. However, the mechanisms behind this observation remain elusive. Our objective was to establish a preclinical model able to recapitulate this phenomenon and investigate the role of immunity underlying such protection. Methods...

article

Evidence for the intrusion of marine Atlantic waters into the West Siberian Arctic during the Middle Pleistocene

Dmitry V. Nazarov, Olga A. Nikolskaia, Anna S. Gladysheva, Igor V. Zhigmanovskiy, more

Boreas > 51 > 2 > 402 - 425

Marine sediments occupy a significant portion of the Quaternary succession in the West Siberian Arctic but, until recently, their ages and distributions have been strongly debated. Based on new geological, palaeontological and geochronological data obtained within the last decade, we hereby postulate the following: (i) Two different Pleistocene interglacial marine formations are exposed across the...

article

Formation of Molybdenum Blues Particles via the Reduction of Molybdate Solutions with Hydroquinone

M. A. Myachina, N. N. Gavrilova, V. V. Nazarov

Colloid Journal > 2019 > 81 > 5 > 541-545

Dispersions of molybdenum blues have been synthesized by reducing a molybdate with hydroquinone in an acidic medium. Spectrophotometry and photon-correlation spectroscopy have been employed to study the formation regularities of molybdenum blues particles (large molybdenum oxide clusters) under the conditions of varied reductant/molybdate ratio and dispersion medium pH.

article

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients

Petr V. Nazarov, Anke K. Wienecke-Baldacchino, Andrei Zinovyev, Urszula Czerwińska, more

BMC Medical Genomics > 2019 > 12 > 1 > 1-17

Background The amount of publicly available cancer-related “omics” data is constantly growing and can potentially be used to gain insights into the tumour biology of new cancer patients, their diagnosis and suitable treatment options. However, the integration of different datasets is not straightforward and requires specialized approaches to deal with heterogeneity at technical and biological levels...

article

Dehydrogenation of Methylbutenes to Isoprene: A Comparative Mathematical Analysis of the Dehydrogenation of Methylbutenes to Isoprene in Axial and Radial Reactors

B. Sh. Gilmurakhmanov, P. V. Urtyakov, M. V. Nazarov, O. S. Roshchina, more

Catalysis in Industry > 2019 > 11 > 2 > 162-167

Using a mathematical model that describes the process of methylbutene dehydrogenation to isoprene, a comparative analysis of energy efficiency is performed for two upgrading variants: (1) a system of two serially arranged axial fixed-bed reactors and (2) an adiabatic fixed-bed reactor. A mathematical analysis is performed to determine the dependence of yield Y and selectivity S on quantity Q of thermal...

article

Calculating the Index of Volatility in Inhomogeneous Levy Models

A. S. Kuvaev, L. V. Nazarov

Moscow University Computational Mathematics and Cybernetics > 2019 > 43 > 2 > 74-81

The problem of calculating an analog of volatility index (VIX) in exponential Levy models is considered. To obtain the relation for the original index, an assumption is made about the market diffusion model. Unlike Levy models, diffusion models are not able to describe sharp changes of asset prices and offer a poorer calibration flexibility. Relations for calculating an analog of VIX for the exponential...

article

A Small Antenna Feeder System of an EHF Radio-Interferometer for Diagnostics of Gas-Dynamic Processes in Closed Volumes

Ye. Yu. Gaynulina, A. V. Kashin, N. S. Kornev, A. V. Nazarov

Instruments and Experimental Techniques > 2019 > 62 > 3 > 366-372

This article presents the design of an antenna feeder system (AFS) for extremely-high-frequency radio interferometers equipped with a small transmitter, which is intended for diagnostics of fast gas-dynamic processes in closed volumes with a limited internal space . Numerical simulation and experimental studies proved the fundamental possibility of developing an AFS with an aperture size that does...

article

Synthetic modification and cytotoxic evaluation of 2-cyano-3,4-secotriterpenic methylketones

Alexey V. Nazarov, Irina A. Tolmacheva, Anastasia E. Zhukova, Victoria V. Grishko

Chemical Papers > 2019 > 73 > 7 > 1767-1775

Triterpenic methylketones, known earlier and obtainable as a result of oxidative transformation of double bond(s) in 2-cyano-3,4-secoderivatives of the lupane and 18αH-oleanane types, can be regarded as promising intermediates for synthetic transformation. This study has demonstrated the acid-catalyzed α-bromination of methylketones as capable of providing a series of various bromine-substituted ketones...

article

In Situ Modification and Analysis of the Composition and Crystal Structure of a Silicon Target by Ion-Beam Methods

Yu. V. Balakshin, A. A. Shemukhin, A. V. Nazarov, A. V. Kozhemiako, more

Technical Physics > 2018 > 63 > 12 > 1861-1867

The method of Rutherford backscattering (RBS) with channeling is widely used in compositional analysis and structural determination. An experimental process line for in situ ion implantation and RBS spectrometry is presented, and its technical parameters are given. The parameters of a probing beam needed to reach a several-percent error in the study of distribution profiles of impurities and defects...

article

Features of Wave Propagation in an Inhomogeneous Plasma near the Electron Cyclotron Resonance

M. S. Malyshev, V. V. Nazarov, A. V. Kostrov, A. G. Galka

JETP Letters > 2019 > 110 > 4 > 262-265

Features of the propagation of electromagnetic waves in an inhomogeneous plasma at frequencies close to the electron-cyclotron resonance have been studied experimentally. It has been established that the main flux of electromagnetic radiation near the cyclotron resonance is perpendicular to the magnetic field lines. The amplitude of this radiation reaches a maximum at a plasma frequency ω_pe of about...

article

Measurement of the Brightness Temperature of the Fast Gas-Dynamics Processes using the EHF Radiointerferometer Radiometer in the Presence of Active-Channel Signal

E. V. Botov, V. N. Ikonnikov, V. A. Kanakov, N. S. Kornev, more

Radiophysics and Quantum Electronics > 2018 > 61 > 5 > 382-388

We show the results of simultaneous measurements of the brightness temperature and the detonation-front motion in a trinitrotoluene sample. The measurements were performed using the EHF radiointerferometer radiometer developed at Yu. E. Sedakov Research Institute of Measurement Systems. The algorithms and the methods for the recorded-signal processing are described.

article

Measurement of Kinematic and Thermal Characteristics of High-Speed Gas-Dynamic Processes by Means of Microwave Sounding

E. V. Botov, V. N. Ikonnikov, V. A. Kanakov, N. S. Kornev, more

Combustion, Explosion, and Shock Waves > 2018 > 54 > 5 > 614-617

The paper describes a method of simultaneous measurements of kinematic parameters of a high-speed process by a microwave radio interferometer with a 3-mm range of wavelengths and the brightness temperature of the same process by the microwave radio interferometer operating in the radiometer mode. The methods of radiometer calibration and analysis of radiometric data are described. Results of experimental...

article

Formation of Molybdenum Blue Particles via the Reduction of a Molybdate Solution with Glucose

M. A. Myachina, N. N. Gavrilova, V. V. Nazarov

Russian Journal of Physical Chemistry A > 2018 > 92 > 11 > 2237-2241

Molybdenum blue dispersions are synthesized via the reduction of molybdate with glucose in an acidic medium. Spectrophotometry and photon correlation spectroscopy show that, depending on the reducing agent/molybdate ratio and the pH value, both colored complex Mo compounds and dispersed phase particles (large molybdenum oxide clusters) can form. It is shown that particles form in the 1.4–2.2 range...

article

Sol–Gel Synthesis of Membrane Mo₂C/Al₂O₃ Catalysts with Different Architectures and Their Catalytic Activity in the Reaction of Carbon Dioxide Conversion of Methane

N. N. Gavrilova, M. A. Myachina, D. V. Ardashev, V. V. Nazarov, more

Kinetics and Catalysis > 2018 > 59 > 5 > 635-643

The methods of synthesis of composite membrane catalysts based on Mо₂C and Al₂O₃ support by a sol–gel method were developed. The samples of membrane catalysts with different architectures were developed. The difference in the catalytic activity of membrane catalysts in carbon dioxide conversion of methane depending on the porous structure and morphology of the catalytic layer was studied.

article

Developing a Machining Strategy for Hard-Alloy Polyhedral Inserts on CNC Grinding and Sharpening Machines

E. V. Vasil’ev, A. Yu. Popov, A. A. Lyashkov, P. V. Nazarov

Russian Engineering Research > 2018 > 38 > 8 > 642-644

Methods of grinding and shaping the rear surface of hard-alloy polyhedral inserts are considered. Machining of the tool’s rear surface is simulated, and several kinematic configurations for margin removal are proposed. An algorithm for kinematic shaping of the rear surface of a hard-alloy polyhedral insert in CAD systems is outlined.

article

Simulation of Structure Formation in Shaped Rolled Steel in the Process of Its Heat Treatment

A. B. Sychkov, A. B. Moller, D. V. Nazarov, G. Ya. Kamalova, more

Metallurgist > 2018 > 62 > 3-4 > 193-202

We present the results of development of the technology of thermal hardening and thermal straightening of shaped rolled St3 steel (structural angles) based on the mathematical and physical simulation of the process of heat transfer with accelerated water cooling of the metal. For this purpose, we used the DEFORM 3D + HEAT TREATMENT software environment of the finite-element method and carried out...

article

Sol–Gel Synthesis and Distinctive Structural Features of Ce_xZr_1–xO₂ Solid Solutions

N. N. Gavrilova, V. V. Nazarov

Inorganic Materials > 2018 > 54 > 8 > 831-839

We have synthesized Ce_xZr_1–xO₂ solid solutions via the thermal decomposition of xerogels of different compositions prepared by drying appropriate hydrosols. The synthesized materials have been characterized by thermal analysis, X-ray diffraction, and Raman spectroscopy. The results demonstrate that the solid solutions are formed at relatively low temperatures (450–600°C). The Ce_xZr_1–xO₂ samples with...

article

Temperature Distribution Measurement in Polymer Composite Pipes During Their Heat Treatment with the Use of Microwave Radiation

V. N. Nefedov, A. V. Mamontov, V. P. Simonov, I. V. Nazarov

Measurement Techniques > 2018 > 61 > 3 > 265-270

A method is proposed for constructing radial type microwave devices forming a uniform temperature distribution throughout the volume of pipes made of polymer composite materials The results of theoretical and experimental investigations of the temperature distribution across the thickness of the pipe material are given. The advantages of microwave technologies for curing polymer composite materials...

article

Synthesis and Antibacterial Activity of 9-Oxo-9,10-dihydroacridinecarboxylic Acids Esters Bearing a Triazole Fragment

T. N. Kudryavtseva, A. Yu. Lamanov, L. G. Klimova, G. V. Nazarov

Russian Journal of General Chemistry > 2018 > 88 > 4 > 676-681

An effective method for the synthesis of new acridine-9(10H)-one (acridone) derivatives containing 1,2,3-triazole fragment was developed. A number of new triazole-containing compounds were synthesized from propargyl acridone acetate and their antimicrobial activity was studied.

article

Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach

Léon-Charles Tranchevent, Petr V. Nazarov, Tony Kaoma, Georges P. Schmartz, more

Biology Direct > 2018 > 13 > 1 > 1-13

Background One of the main current challenges in computational biology is to make sense of the huge amounts of multidimensional experimental data that are being produced. For instance, large cohorts of patients are often screened using different high-throughput technologies, effectively producing multiple patient-specific molecular profiles for hundreds or thousands of patients. Results We propose...

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INFONA - science communication portal

Search results for: V. Nazarov

Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice

Evidence for the intrusion of marine Atlantic waters into the West Siberian Arctic during the Middle Pleistocene

Formation of Molybdenum Blues Particles via the Reduction of Molybdate Solutions with Hydroquinone

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients

Dehydrogenation of Methylbutenes to Isoprene: A Comparative Mathematical Analysis of the Dehydrogenation of Methylbutenes to Isoprene in Axial and Radial Reactors

Calculating the Index of Volatility in Inhomogeneous Levy Models

A Small Antenna Feeder System of an EHF Radio-Interferometer for Diagnostics of Gas-Dynamic Processes in Closed Volumes

Synthetic modification and cytotoxic evaluation of 2-cyano-3,4-secotriterpenic methylketones

In Situ Modification and Analysis of the Composition and Crystal Structure of a Silicon Target by Ion-Beam Methods

Features of Wave Propagation in an Inhomogeneous Plasma near the Electron Cyclotron Resonance

Measurement of the Brightness Temperature of the Fast Gas-Dynamics Processes using the EHF Radiointerferometer Radiometer in the Presence of Active-Channel Signal

Measurement of Kinematic and Thermal Characteristics of High-Speed Gas-Dynamic Processes by Means of Microwave Sounding

Formation of Molybdenum Blue Particles via the Reduction of a Molybdate Solution with Glucose

Sol–Gel Synthesis of Membrane Mo₂C/Al₂O₃ Catalysts with Different Architectures and Their Catalytic Activity in the Reaction of Carbon Dioxide Conversion of Methane

Developing a Machining Strategy for Hard-Alloy Polyhedral Inserts on CNC Grinding and Sharpening Machines

Simulation of Structure Formation in Shaped Rolled Steel in the Process of Its Heat Treatment

Sol–Gel Synthesis and Distinctive Structural Features of Ce_xZr_1–xO₂ Solid Solutions

Temperature Distribution Measurement in Polymer Composite Pipes During Their Heat Treatment with the Use of Microwave Radiation

Synthesis and Antibacterial Activity of 9-Oxo-9,10-dihydroacridinecarboxylic Acids Esters Bearing a Triazole Fragment

Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach

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