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Optical fibers (core diameter 8μm, cladding diameter 125μm) was tapered to a waist diameter in the range of 8–12μm, and then a monoclonal antibody to the pathogen, Escherichia coli O157:H7 was covalently bonded to the surface of the tapered region. Using 470nm light, the taper was exposed to various concentrations (7×10 7 , 7×10 5 , 7×10 3 , and 70cells/mL) of the pathogen,...
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