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Proteine In der Zuschrift auf S. 2386 ff. schildern V. Forge, R. Antoine et al. den Einsatz der Ladungsdetektions‐Massenspektrometrie zur Charakterisierung von Amyloidfibrillen. Mit dieser Methode kann die Proteinaggregation in Echtzeit verfolgt werden.
Amyloid fibrils are self‐assembled protein structures with important roles in biology (either pathogenic or physiological), and are attracting increasing interest in nanotechnology. However, because of their high aspect ratio and the presence of some polymorphism, that is, the possibility to adopt various structures, their characterization is challenging and basic information such as their mass is...
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