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Reactions of metal chloride or sulfate and the sodium salt of 5-nitrosalicylic acid (5-nsa) in aqueous solution result in isomorphous complexes of type [M(H 2 O) 5 (5-nsa)] + (5-nsa) − ·H 2 O [M=Mg (1), Zn (2), Co (3), Ni (4)] in the solid state. Structural analyses of these compounds reveal that the cationic moiety is a monomeric complex in which the metal...
Purpose. In the route of developing novel liquid phase formulations based on the encapsulation of busulfan into liposomes in nontoxic solvents, drug crystallization inevitably occurs. In order to better understand the reactivity of busulfan, the characterization of its molecular properties was therefore considered as a key point. Also, preliminary attempts to prevent...
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