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Multifunctional colloidal core-shell nanoparticles of magnetic nanocrystals (of iron oxide or FePt) or gold nanorods encapsulated in silica shells doped with the fluorescent dye, Tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate (Rubpy) were synthesized. The as-prepared magnetic nanocrystals are initially hydrophobic and were coated with silica using a microemulsion approach, while the as-prepared...
We report strong two-photon-induced photoluminescence (TPIP) from silica/gold nanoshells (NS). We demonstrate its potential application for imaging the 3D distribution of NS in tumors using a NIR laser scanning multi-photon microscope.
We present two-photon luminescence (TPL) imaging of cancer cells through a 10 × 15 × 40 mm3 miniaturized probe employing a two-axis MEMS scanning mirror and an air-core photonic crystal fiber. The combination of TPL imaging with a small probe represents a potential method of distinguishing cancerous cells in tissue for diagnosis.
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