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The Menkes (MNK) and Wilson (WLN) disease proteins are two P‐type ATPases responsible for active Cu efflux. These ATPases are also associated with resistance to cisplatin. In this work, different metal‐binding domains (MBDs) of ATPases (9 out of 12 domains) were compared based on their reactivity towards cisplatin. The reaction rates of the MBDs can be largely different; the reaction of MNK6 is about...
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