Search results for: Susanna Herold

Items from 1 to 20 out of 32 results

article

NO ^• Release from MbFe(II)NO and HbFe(II)NO after Oxidation by Peroxynitrite

Susanna Herold, Francesca Boccini

Inorganic Chemistry > 2006 > 45 > 17 > 6933 - 6943

article

Pulse Radiolysis Studies of the Reactions of CO ₃ ^•- and NO ₂ ^• with Nitrosyl(II)myoglobin and Nitrosyl(II)hemoglobin

Francesca Boccini, Anastasia S. Domazou, Susanna Herold

The Journal of Physical Chemistry A > 2006 > 110 > 11 > 3927 - 3932

article

Peroxynitrite efficiently mediates the interconversion of redox intermediates of myeloperoxidase

Paul Georg Furtmüller, Walter Jantschko, Martina Zederbauer, Manfred Schwanninger, more

Biochemical and Biophysical Research Communications > 2005 > 337 > 3 > 944-954

Nitric oxide-derived oxidants (e.g., peroxynitrite) are believed to participate in antimicrobial activities as part of normal host defenses but also in oxidative tissue injury in inflammatory disorders. A similar role is ascribed to the heme enzyme myeloperoxidase (MPO), the most abundant protein of polymorphonuclear leukocytes, which are the terminal phagocytosing effector cells of the innate immune...

article

Reactions of peroxynitrite with globin proteins and their possible physiological role

Susanna Herold, Angela Fago

Comparative Biochemistry and Physiology, Part A > 2005 > 142 > 2 > 124-129

It is now widely accepted that, besides their well-established function in O ₂ transport, hemoglobin and myoglobin also undergo several redox reactions aimed to scavenge toxic free radicals and reactive oxygen and nitrogen species. At least some of these reactions are believed to play an important physiological role in the defense against oxidative stress. This aspect is exemplified by the...

article

Mechanistic studies of S-nitrosothiol formation by NO/O2 and by NO/methemoglobin

Susanna Herold, Gabriele Röck

Archives of Biochemistry and Biophysics > 2005 > 436 > 2 > 386-396

The mechanisms of formation of S-nitrosothiols under physiological conditions and, in particular, of generation of SNO-Hb (the hemoglobin form in which the cysteine residues β93 are S-nitrosated) are still not completely understood. In this paper, we investigated whether, in the presence of O ₂ , NO is more efficient to nitrosate protein-bound thiols such as Cysβ93 or low molecular weight...

article

Mechanistic Studies of the Oxygen-Mediated Oxidation of Nitrosylhemoglobin ^†

Susanna Herold, Gabriele Röck

Biochemistry > 2005 > 44 > 16 > 6223 - 6231

article

Ligand Binding Properties of Bacterial Hemoglobins and Flavohemoglobins ^†

Judith Farrés, Markus P. Rechsteiner, Susanna Herold, Alexander D. Frey, more

Biochemistry > 2005 > 44 > 10 > 4125 - 4134

article

Peroxynitritometal complexes

Susanna Herold, Willem H. Koppenol

Coordination Chemistry Reviews > 2005 > 249 > 3-4 > 499-506

Peroxynitrite as a ligand can be formed (1) from the reaction of a superoxometal complex with nitrogen monoxide, or (2) as an intermediate in the catalysis of the isomerization to nitrate or the reduction to nitrogen dioxide. With one exception, namely [(CN) ₅ ONOOCo] ³⁻ , such complexes have not been isolated. The instances where peroxynitrito complexes have been described or invoked...

article

Kinetics and mechanistic studies of the reactions of metleghemoglobin, ferrylleghemoglobin, and nitrosylleghemoglobin with reactive nitrogen species

Susanna Herold, Alain Puppo

JBIC Journal of Biological Inorganic Chemistry > 2005 > 10 > 8 > 946-957

It is now established that nitrogen monoxide is produced not only in animals but also in plants. However, much less is known about the pathways of generation and the functions of $${\text{NO}}^ \bullet $$ in planta. One of the possible targets of $${\text{NO}}^ \bullet $$ is leghemoglobin (Lb), the hemoprotein found in high concentrations in the root nodules of legumes that establish a symbiosis...

article

Oxyleghemoglobin scavenges nitrogen monoxide and peroxynitrite: a possible role in functioning nodules?

Susanna Herold, Alain Puppo

JBIC Journal of Biological Inorganic Chemistry > 2005 > 10 > 8 > 935-945

It has been demonstrated that the NO^• produced by nitric oxide synthase or by the reduction of nitrite by nitrate reductase plays an important role in plants’ defense against microbial pathogens. The detection of nitrosyl Lb in nodules strongly suggests that NO^• is also formed in functional nodules. Moreover, NO^• may react with superoxide (which has been shown to be produced in nodules by various...

article

Mechanistic Studies of the Oxidation of Oxyhemoglobin by Peroxynitrite ^†

Francesca Boccini, Susanna Herold

Biochemistry > 2004 > 43 > 51 > 16393 - 16404

article

Pulse Radiolysis Studies of the Reactions of Carbonate Radical Anion with Myoglobin and Hemoglobin

Francesca Boccini, Anastasia S. Domazou, Susanna Herold

The Journal of Physical Chemistry A > 2004 > 108 > 27 > 5800 - 5805

article

Mechanistic Studies of the Isomerization of Peroxynitrite to Nitrate Catalyzed by Distal Histidine Metmyoglobin Mutants

Susanna Herold, Shivashankar Kalinga, Toshitaka Matsui, Yoshihito Watanabe

Journal of the American Chemical Society > 2004 > 126 > 22 > 6945 - 6955

article

The Outer-Sphere Oxidation of Nitrosyliron(II)hemoglobin by Peroxynitrite Leads to the Release of Nitrogen Monoxide

Susanna Herold

Inorganic Chemistry > 2004 > 43 > 13 > 3783 - 3785

article

Nitrotyrosine, dityrosine, and nitrotryptophan formation from metmyoglobin, hydrogen peroxide, and nitrite

Susanna Herold

Free Radical Biology and Medicine > 2004 > 36 > 5 > 565-579

The biological relevance of tyrosine nitration is a subject of much interest, because extensive evidence supports formation of 3-nitrotyrosine in vivo under a variety of different pathological conditions. Several reagents are likely to be responsible for nitration in vivo, among others peroxynitrite and nitrite in the presence of H ₂ O ₂ /peroxidases. In this work we show that also...

article

Metmyoglobin and Methemoglobin Catalyze the Isomerization of Peroxynitrite to Nitrate ^†

Susanna Herold, Kalinga Shivashankar

Biochemistry > 2003 > 42 > 47 > 14036 - 14046

article

Interaction du monoxyde d'azote avec l'hemoglobine et la production artefactuelle de S-nitroso-hemoglobine

Susanna Herold

Comptes rendus - Biologies > 2003 > 326 > 6 > 533-541

Hemoglobin (Hb) is probably the most thoroughly studied protein in the human body. However, it has recently been proposed that in addition to the well known function of dioxygen and carbon dioxide transporter, one of the main roles of hemoglobin is to store and transport nitrogen monoxide. This hypothesis is highly disputed and is in contrast to the proposal that hemoglobin serves as an NO ^* ...

article

The Mechanism of the Peroxynitrite-Mediated Oxidation of Myoglobin in the Absence and Presence of Carbon Dioxide

Susanna Herold, Michael Exner, Francesca Boccini

Chemical Research in Toxicology > 2003 > 16 > 3 > 390 - 402

article

Kinetics of the reactions of nitrogen monoxide and nitrite with ferryl hemoglobin

Susanna Herold, Franz-Josef K. Rehmann

Free Radical Biology and Medicine > 2003 > 34 > 5 > 531-545

Hemoglobin released in the circulation from ruptured red blood cells can be oxidized by hydrogen peroxide or peroxynitrite to generate the highly oxidizing iron(iv)oxo species HbFe ⁱ ^v O. Nitrogen monoxide, produced in large amounts by activated inducible nitric oxide synthase, can have indirect cytotoxic effects, mainly through the generation of peroxynitrite from its very fast reaction...

article

Myoglobin Scavenges Peroxynitrite without Being Significantly Nitrated

Susanna Herold, Kalinga Shivashankar, Martin Mehl

Biochemistry > 2002 > 41 > 45 > 13460 - 13472

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Susanna Herold

NO ^• Release from MbFe(II)NO and HbFe(II)NO after Oxidation by Peroxynitrite

Pulse Radiolysis Studies of the Reactions of CO ₃ ^•- and NO ₂ ^• with Nitrosyl(II)myoglobin and Nitrosyl(II)hemoglobin

Peroxynitrite efficiently mediates the interconversion of redox intermediates of myeloperoxidase

Reactions of peroxynitrite with globin proteins and their possible physiological role

Mechanistic studies of S-nitrosothiol formation by NO/O2 and by NO/methemoglobin

Mechanistic Studies of the Oxygen-Mediated Oxidation of Nitrosylhemoglobin ^†

Ligand Binding Properties of Bacterial Hemoglobins and Flavohemoglobins ^†

Peroxynitritometal complexes

Kinetics and mechanistic studies of the reactions of metleghemoglobin, ferrylleghemoglobin, and nitrosylleghemoglobin with reactive nitrogen species

Oxyleghemoglobin scavenges nitrogen monoxide and peroxynitrite: a possible role in functioning nodules?

Mechanistic Studies of the Oxidation of Oxyhemoglobin by Peroxynitrite ^†

Pulse Radiolysis Studies of the Reactions of Carbonate Radical Anion with Myoglobin and Hemoglobin

Mechanistic Studies of the Isomerization of Peroxynitrite to Nitrate Catalyzed by Distal Histidine Metmyoglobin Mutants

The Outer-Sphere Oxidation of Nitrosyliron(II)hemoglobin by Peroxynitrite Leads to the Release of Nitrogen Monoxide

Nitrotyrosine, dityrosine, and nitrotryptophan formation from metmyoglobin, hydrogen peroxide, and nitrite

Metmyoglobin and Methemoglobin Catalyze the Isomerization of Peroxynitrite to Nitrate ^†

Interaction du monoxyde d'azote avec l'hemoglobine et la production artefactuelle de S-nitroso-hemoglobine

The Mechanism of the Peroxynitrite-Mediated Oxidation of Myoglobin in the Absence and Presence of Carbon Dioxide

Kinetics of the reactions of nitrogen monoxide and nitrite with ferryl hemoglobin

Myoglobin Scavenges Peroxynitrite without Being Significantly Nitrated

Filter options

Publication date

Content availability

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Susanna Herold

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options