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Both biological and model liposomal membranes have unequal distribution of molecular components in the plane of the membrane. There is increasing interest to determine the composition and properties of membrane domains enriched with specific molecular components. Several methodologies have been applied to study this. Each has its own advantages and provides a particular kind of information. In the...
Samples of dimyristoylphosphatidylglycerol and dimyristoylphosphatidylserine which exhibit highly cooperative phase transitions in suspension with 0.5 M NaCl, 10 mM sodium phosphate, pH 7.0, demonstrate a marked broadening of the phase transition when suspended in distilled water at pH 7. The cooperativity of the thermal transition of dimyristoylphosphatidic acid at pH 7.0, in contrast, was little...
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