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A new non-ionic nucleoside based lipid (DOU-SS-PEG 2000 , 5′-PEG 2000 -2′,3′-dioleoyluridine) featuring uridine (U) as nucleoside and 2′,3′-dioleyl (DO), as lipid moieties and a poly(ethylene glycol) (PEG) thiolytic cleavable spacer for in vitro delivery of drugs is described. The PEG detachable nucleotide lipid (DOU-SS-PEG 2000 ) was prepared via a convergent synthesis starting...
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