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Transforming growth factor beta 1 (TGF-β1) plays an important role in the development of radiation- and drug-induced organ diseases. Proteinases-activated receptor 1 (PAR-1) is involved in many pathophysiologic processes after its activation by serine proteases. The aim of the present study was to determine messenger RNA (mRNA) production of TGF-β1 and PAR-1 in the lungs after local irradiation. Mice...
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