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Extracellular matrices (ECM) rich in type I collagen exhibit characteristic anisotropic ultrastructures. Nevertheless, working in vitro with this biomacromolecule remains challenging. When processed, denaturation of the collagen molecule is easily induced in vitro avoiding proper fibril self‐assembly and further hierarchical order. Here, an innovative approach enables the production of highly concentrated...
In article number 1902224, Bernard Coulomb, Nadine Nassif, and co‐workers propose an innovative spray‐processing approach, allowing fast and cheap production of highly concentrated, self‐assembled type I collagen microparticles. The native properties of collagen are preserved, further enabling the encapsulation of therapeutic biomolecules and their injection for potential active tissue regeneration...
The elaboration of metabolically active cell‐containing materials is a decisive step toward the successful application of cell based technologies. The present work unveils a new process allowing to simultaneously encapsulate living cells and shaping cell‐containing materials into solid‐state macroporous foams with precisely controlled morphology. Our strategy is based on freeze casting, an ice templating...
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