Search results for: Katarzyna Kurzatkowska

Items from 1 to 11 out of 11 results

article

Plasmonic nanocarrier grid-enhanced Raman sensor for studies of anticancer drug delivery

Katarzyna Kurzątkowska, Ty Santiago, Maria Hepel

Biosensors and Bioelectronics > 2017 > 91 > C > 780-787

Targeted drug delivery systems using nanoparticle nanocarriers offer remarkable promise for cancer therapy by discriminating against devastating cytotoxicity of chemotherapeutic drugs to healthy cells. To aid in the development of new drug nanocarriers, we propose a novel plasmonic nanocarrier grid-enhanced Raman sensor which can be applied for studies and testing of drug loading onto the nanocarriers,...

article

Voltammetric detection of the S100B protein using His-tagged RAGE domain immobilized onto a gold electrode modified with a dipyrromethene–Cu(II) complex and different diluents

Katarzyna Kurzątkowska, Agata Jankowska, Aleksandra Wysłouch-Cieszyńska, Liliya Zhukova, more

Journal of Electroanalytical Chemistry > 2016 > 767 > C > 76-83

In this work, we report on the His-tagged VC1 natural domain of the Receptor for Advanced Glycation End Products (RAGE) for the electrochemical determination of the S100 beta calcium binding protein (S100B). The domain was covalently immobilized on a layer of the thiol derivative of a dipyrromethene (DPM) complex with copper(II) ions, previously deposited on the gold electrode surface. The changes...

article

Calix[4]arene derivatives as dopamine hosts in electrochemical sensors

Katarzyna Kurzątkowska, Serkan Sayin, Mustafa Yilmaz, Hanna Radecka, more

Sensors and Actuators B: Chemical > 2015 > 218 > C > 111-121

In this work, we introduce the use of an electrochemical sensor based on ion-channel mechanism in order to investigate the interaction between different-functionalized calixarene mercaptoalkyl derivatives and dopamine at the aqueous/organic interface. Three different calix[4]arene derivatives, functionalized with mercaptoalky groups at the upper-rim of calix[4]arene, were synthesized, and their structures...

article

Immobilization of His-tagged kinase JAK2 onto the surface of a plasmon resonance gold disc modified with different copper (II) complexes

Katarzyna Kurzątkowska, Marcin Mielecki, Krystyna Grzelak, Peter Verwilst, more

Talanta > 2014 > 130 > Complete > 336-341

New surface plasmon resonance (SPR) sensing platforms which consists of copper (II) complexes of a pentetic acid thiol ligand (DPTA-Cu(II)) and of a thiol derivative of dipyrromethene (DPM-Cu(II) created on the surface of gold SPR disc were applied to oriented immobilization of His-tagged Janus kinase 2 (GST-His ₆ -JAK2). This method is based on the covalent bond formation between histidine...

article

Pentetic acid (DPTA) Cu(II) monolayer deposited on gold electrode—The base of biosensors for electrochemical screening of kinase JAK2 and potential inhibitor interactions

Justyn Wojtasik, Marcin Mielecki, Katarzyna Kurzątkowska, Krystyna Grzelak, more

Sensors and Actuators B: Chemical > 2014 > 196 > C > 223-230

Here, the new biosensor destined for screening of interactions between kinase JAK2 and compounds which may act as inhibitors was presented. The Cu(II) complex of pentetic acid thiol ligand was applied for immobilization of kinase JAK2 on the gold electrode surface through his-tagged chemistry. The base of the biosensor response was the change of the electrochemical properties of the Cu(II) redox centres...

article

Electrochemical sensing of 2D condensation in amyloid peptides

Katarzyna Kurzątkowska, Veronika Ostatná, Ian W. Hamley, Thomas Doneux, more

Electrochimica Acta > 2013 > 106 > Complete > 43-48

The interfacial behavior of the model amyloid peptide octamer YYKLVFFC (peptide 1) and two other amyloid peptides YEVHHQKLVFF (peptide 2) and KKLVFFA (peptide 3) at the metal|aqueous solution interface was studied by voltammetric and constant current chronopotentiometric stripping (CPS). All three peptides are adsorbed in a wide potential range and exhibit different interfacial organizations depending...

article

Oriented immobilization of His-tagged kinase RIO1 protein on redox active N-(IDA-like)-Cu(II) monolayer deposited on gold electrode—The base of electrochemical biosensor

Marcin Mielecki, Justyn Wojtasik, Magdalena Zborowska, Katarzyna Kurzątkowska, more

Electrochimica Acta > 2013 > 96 > Complete > 147-154

The fabrication of electrochemical biosensor consists of the following successive steps: formation of thiol derivative of iminodiacetic acid (IDA-like/N-heterocyclic donor) and N-acetylcysteamine (NAC) self-assembled monolayer on the Au electrode, complexation of Cu(II) by N(IDA-like) attached to the surface of the Au electrode and immobilization of kinase protein Rio1 through N(IDA-like)-Cu(II)-histidine-tag...

article

Native and denatured forms of proteins can be discriminated at edge plane carbon electrodes

Veronika Ostatná, Hana Černocká, Katarzyna Kurzątkowska, Emil Paleček

Analytica Chimica Acta > 2012 > 735 > Complete > 31-36

In an attempt to develop a label-free electrochemical method for detection of changes in protein structures based on oxidizability of tyrosine and tryptophan residues we tested different types of carbon electrodes. We found that using edge plane pyrolytic graphite electrode (EPGE) we can discriminate between native and denatured forms of human serum albumin (HSA) and of other proteins, such as bovine...

chapter

Electrochemical sensing of proteins and carbohydrates

Emil Paleček, Veronika Ostatná, Mojmír Trefulka, Martin Bartošik, more

2010 IEEE Sensors > 833 - 836

2010 Ninth IEEE Sensors Conference (SENSORS 2010)

We invented an electrocatalytic chronopotentiometric stripping (CPS) method for the analysis of virtually all proteins at femtomole level. Sensitivity of this method to changes in protein structures was applied in biomedicine. Polysaccharides and ribose at the 3'-end of RNA can be modified by some Os complexes and detected electrochemically directly in the reaction mixture at nanomolar and subnanomolar...

article

Gold Electrode Incorporating Corrole as an Ion-Channel Mimetic Sensor for Determination of Dopamine

Katarzyna Kurzatkowska, Eduard Dolusic, Wim Dehaen, Karolina Sieroń-Stołtny, more

Analytical Chemistry > 2009 > 81 > 17 > 7397 - 7405

article

Iron (III) porphyrin bearing 2,6-di-tert-butylphenol pendants deposited onto gold electrodes for amperometric determination of l-histidine

Katarzyna Kurzątkowska, Dmitry Shpakovsky, Jerzy Radecki, Hanna Radecka, more

Talanta > 2009 > 78 > 1 > 126-131

A sensitive amperometric sensor for determination of l-histidine was developed using gold electrode modified with Fe(III)-porphyrin bearing three 2,6-di-tert-butylphenol groups and one palmitoyl chain. Two methods of electrode modification were applied: direct chemisorption and embedment into dodecanethiol monolayer. Both types of electrodes were used for detection of l-histidine using Osteryoung...

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Keywords

ELECTROCHEMICAL BIOSENSOR (2)
HIS-TAGGED PROTEIN IMMOBILIZATION (2)
2D CONDENSED LAYERS (1)
ALZHEIMER'S DISEASE (1)
AMYLOID PEPTIDE SENSING (1)
AUNP NANOCARRIERS (1)
BIOCHEMISTRY (1)
BIOSENSORS (1)
CALIXARENE (1)
CARBOHYDRATES (1)
CARBON ELECTRODES (1)
CATALYTIC HYDROGEN EVOLUTION (1)
CPS METHOD (1)
CU(II) REDOX-ACTIVE MONOLAYER (1)
DERIVATIVE OF IMINODIACETIC ACID-CU(II) COMPLEX FORMATION (1)
DIPYRROMETHENE-CU(II) (1)
DIPYRROMETHENE–CU(II) COMPLEX (1)
DOPAMINE (1)
EDGE PLANE PYROLYTIC GRAPHITE (1)
ELECTRIC POTENTIAL (1)
ELECTROCATALYTIC CHRONOPOTENTIOMETRIC STRIPPING (1)
ELECTROCHEMICAL BIOSENSORS (1)
ELECTROCHEMICAL SENSING (1)
ELECTROCHEMICAL SENSORS (1)
ELECTRODES (1)
ELECTROOXIDATION OF PROTEINS (1)
GEMCITABINE DRUG RELEASE (1)
GENOMICS (1)
GOLD ELECTRODES (1)
HIS-TAGGED KINASE JAK2 IMMOBILIZATION (1)
HIS-TAGGED RAGE RECEPTOR (1)
HISTIDINE (1)
HUMAN SERUM ALBUMIN (1)
ION-CHANNEL MIMETIC SENSORS (1)
IRON(III) PORPHYRIN (1)
JANUS KINASE 2 (1)
KINASE JAK2–POTENTIAL INHIBITOR INTERACTIONS (1)
KINETIC AND THERMODYNAMIC ANALYSIS (1)
MERCURY (METALS) (1)
MERCURY–SULFUR BINDING (1)
MOLECULAR BIOPHYSICS (1)
MOLECULAR RECOGNITION (1)
OS COMPLEXES (1)
OSTERYOUNG SQUARE-WAVE VOLTAMMETRY (1)
PENTETIC ACID THIOL LIGAND (1)
PENTETIC ACID THIOL LIGAND-CU(II) (1)
PLASMONIC NANOGRID SENSOR (1)
POLYSACCHARIDES (1)
PROTEIN DENATURATION (1)
PROTEIN STRUCTURE CHANGES (1)
PROTEINS (1)
PROTEIN–SMALL MOLECULE INTERACTIONS (1)
REDOX-ACTIVE MONOLAYER (1)
RIBOSE (1)
RNA (1)
S100B PROTEIN (1)
SENSITIVITY (1)
SENSORS (1)
SERS (1)
SURFACE PLASMON RESONANCE BIOSENSORS (1)
SYNTHESIS (1)
VOLTAMMETRIC AND CHRONOPOTENTIOMETRIC STRIPPING (1)
VOLTAMMETRIC SENSORS (1)
VOLTAMMETRY (CHEMICAL ANALYSIS) (1)
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Elsevier (9)
ACS (1)
ieee (1)

Journal

Electrochimica Acta (2)
Sensors and Actuators B: Chemical (2)
Talanta (2)
Analytica Chimica Acta (1)
Analytical Chemistry (1)
Biosensors and Bioelectronics (1)
Journal of Electroanalytical Chemistry (1)

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Search results for: Katarzyna Kurzatkowska

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