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Serum haptoglobin (Hp), a highly sialylated biomolecule with four N‐glycosylation sites, is a positive acute‐phase response glycoprotein that acts as an immunomodulator. Hp has gained considerable attention due to its potential as a signature molecule that exhibits aberrant glycosylation in inflammatory disorders and malignancies. Its glycosylation can be analyzed qualitatively and quantitatively...
The difficulty of detecting small quantities of contaminants in water supplies currently threatens the health of millions of people worldwide, as consumption of contaminated water has been associated with both cancerous and noncancerous health risks. Existing technologies make it possible to very accurately quantify contaminant levels in water; however the expense, extensive training, and off-site...
In many developing countries, a large percentage of the population lacks access to adequate healthcare. This is especially true in India where close to 70% of the population lives in rural areas and has little to no access to hospitals or clinics. People living in rural India often times cannot afford to pay to see a doctor should they need to make their visits to a hospital. Telemedicine, a breakthrough...
Human breast milk is considered the gold standard for infant nutrition, as breast milk is the only substance that is able to provide infants with the necessary nutrients in their first six months of life. Infants who are fed mother's breast milk are at lower risk for developing a variety of infections and autoimmune diseases and often display better developmental and cognitive performance compared...
Nitrate contamination of groundwater presents a major public health problem in developing countries. Long-term exposure to nitrate causes Blue Baby Syndrome, a leading cause of infant mortality, and various cancers in adults. Spectroscopic nitrate detection methods, while sensitive and accurate, are prohibitively expensive, time consuming and not available at the point of use. Electrochemical detection...
Bacterial contamination of water, for example by Escherichia coli, is a major cause of preventable diseases in rural developing communities. With the lack of infrastructure and experienced laboratory professionals, careful water sampling and analysis becomes inaccessible in these resource-limited environments. There is a need for a low-cost and equipment-free detection platform for detecting pathogens...
Pregnant women in the developing world are often denied the level of healthcare that is needed to prepare them for successful deliveries. Often this inequality of service is due to high costs of medical care, the remote location of patients, and the infrequency of medical visits. We have created a mobile application and added a secure light box that will allow a low-cost implementation of urinalysis...
The difficulty of detecting small quantities of arsenic in water currently threatens the health of millions of people worldwide, as long-term exposure to arsenic has been associated with both cancerous and noncancerous health risks. Existing technologies make it possible to very accurately quantify arsenic levels in water; however the expense, extensive training, and off-site analysis required by...
The difficulty of detecting small quantities of arsenic in water currently threatens the health of millions of people worldwide, as long-term exposure to arsenic has been associated with both cancerous and noncancerous health risks. Existing technologies make it possible to very accurately quantify arsenic levels in water; however the expense, extensive training, and off-site analysis required by...
Arsenic contamination of groundwater presents a major obstacle to the development of water infrastructure in developing countries, with severe long-term health consequences. Current solutions for arsenic testing range from simple colorimetric assays to sophisticated laboratory tests. Colorimetric kits are simple and low-cost, yet these types of tests generally suffer from a lack of precision and use...
Contaminated water is a serious concern in many developing countries with severe health consequences particularly for children. Current methods for monitoring waterborne pathogens are often time consuming, expensive, and labor intensive, making them not suitable for these regions. Electrochemical detection in a microfluidic platform offers many advantages such as portability, minimal use of instrumentation,...
Deteriorating water quality is a serious concern in many developing countries, with severe health consequences especially for children. However, current methods for monitoring waterborne pathogens are often time-consuming, expensive, and labor intensive, which makes them challenging to be implemented in these regions. Toward a solution to this problem, we have demonstrated an electrochemical sensor...
Implantable pumps have allowed for substantial improvements in health and are a developing discipline in biomedical engineering, with applications in drug delivery, fluid removal, and research [1–4]. Towards this end, we here propose a novel electrolytic micropump utilizing a platinum based catalyst for cyclic operation. This pump design offers advantages in terms of low power consumption, high reliability,...
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