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The combination of immunotherapy and chemotherapy to ablate tumors has attracted substantial attention due to the ability to simultaneously elicit antitumor immune responses and trigger direct tumor cell death. However, conventional combinational strategies mainly focus on the employment of drug carriers to deliver immunomodulators, chemotherapeutics, or their combinations, always suffering from complicated...
Benefiting from the admirable energy density (1086 Wh kg−1), overwhelming security, and low environmental impact, rechargeable zinc–air batteries (ZABs) are deemed to be attractive candidates for lithium‐ion batteries. The exploration of novel oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) bifunctional catalysts is the key to promoting the development of zinc–air batteries. Transitional...
As a new type of solution‐processed nano‐laser material, carbon dots (CDs) have shown considerable potential in optical communication, laser displays, micro/nano processing, and biomedicine. Reducing the laser threshold of the gain material is of considerable significance for further development of CDs’ applications in the field of micro/nano lasers. A series of blue‐emissive CDs (B‐CDs) are synthesized...
Centralized Excited States
The decrease in the laser threshold of blue‐emissive carbon dots (B‐CDs) is attributed to the increase in the radiation transition rate and centralized sp3‐related excited state levels, which are favorable for light amplification and population inversion. More details can be found in article number 2207983 by Siyu Lu and co‐workers.
Tactile and Touchless Artificial Skins
In article number 2206830, Yifan Wang and co‐workers present a dual‐responsive artificial skin, which reacts to both pre‐contact events and tactile pressure levels. Overlooked valuable information encoded in the proximal inputs from environments can be explored. Versatile human–machine interfaces (HMIs) for tactile and touchless interactions are achieved. Moreover,...
The progress from intelligent interactions and supplemented/augmented reality requires artificial skins to shift from the single‐functional tactile paradigm. Dual‐responsive sensors that can both detect pre‐contact proximal events and tactile pressure levels enrich the perception dimensions and deliver additional cognitive information. Previous dual‐responsive sensors show very limited utilizations...
Suitable anode materials with high capacity and long cycling stability, especially capability at high current densities, are urgently needed to advance the development of potassium ion batteries (PIBs) and sodium ion batteries (SIBs). Herein, a porous Ni‐doped FeSe2/Fe3Se4 heterojunction encapsulated in Se‐doped carbon (NF11S/C) is designed through selenization of MOFs precursor. The porous composite...
All‐inorganic lead halide perovskite (CsPbX3, X = Cl, Br, I, or their mixture) nanocrystals (NCs) have achieved inspiring advancements in optoelectronic fields but still suffer from poor durability when exposed to environmental stimuli such as water, irradiation and heat. Herein, a strategy of employing pyrophosphate as the inert shell for CsPbX3 NCs is reported. The strong binding between pyrophosphate...
Atherosclerosis Treatment
Herb derived drugs modulate gut microbiome homeostasis and gut‐generated bio‐metabolites. In article number 2105021, Jian‐Dong Jiang, Yongsheng Che, Lu‐Lu Wang, and co‐workers modify the immune cell dynamics and liver function using herb‐derived bicyclol, leading to improved chronic inflammation and cholesterol metabolism. The endothelial activation and cholesterol ester...
Atherosclerosis (AS) is associated with high morbidity and mortality, thus imposing a growing burden on modern society. Herb‐derived bicyclol (BIC) is a versatile bioactive compound that can be used to treat AS. However, its efficacy in AS is not yet described. Here, it is shown that BIC normalizes gut microflora dysbiosis induced by a high fat diet in Apoe(−/−) mice. Metagenome‐wide association study...
Despite the activation of T lymphocytes by antigen‐presenting cells being responsible for eliciting antigen‐specific immune responses, their crosstalking suffers from temporospatial limitations and endogenous influencing factors, which restrict the generation of a strong antitumor immunity. Here, cascade cell membrane coating is reported to prepare biomimetic nanoparticles (BNs) that can manipulate...
Plasmonic nanostructures have raised the interest of biomedical applications of surface‐enhanced Raman scattering (SERS). To improve the enhancement and produce sensitive SERS probes, porous Au–Ag alloy nanoparticles (NPs) are synthesized by dealloying Au–Ag alloy NP‐precursors with Au or Ag core in aqueous colloidal environment through galvanic replacement reaction. The novel designed core–shell...
The biofouling of ureteral stents and subsequent urinary tract infections mainly come from the adsorption and adhesion of proteins and microorganisms and their ensuing proliferation. Although general polycationic surfaces in implants have good antibacterial activities, they suffer from limited durability due to severe protein and bacterial adsorption. Here, a biodegradable and anti‐biofilm fiber‐membrane...
Porous alloy nanomaterials are important for applications in catalysis, sensing, and actuation. Chemical and electrochemical etching are two methods to form porous nanostructures by dealloying bimetallic nanoparticles (NPs). However, it is not clear how the NPs evolve during these etching processes. Insight into the morphological and compositional transformations of the NPs during the etching is critical...
Nanoscale titanium nitride TiN is a metallic material that can effectively harvest sunlight over a broad spectral range and produce high local temperatures via the photothermal effect. Nanoscale indium oxide‐hydroxide, In2O3−x(OH)y, is a semiconducting material capable of photocatalyzing the hydrogenation of gaseous CO2; however, its wide electronic bandgap limits its absorption of photons to the...
Tumor vasculature and cancer stem cells (CSCs) accelerate the development of metastatic renal cancer. Dual inhibition of vascular endothelium and CSCs is still a challenge due to their different pathological features. Herein, a transformable dual‐inhibition system (TDS) based on a self‐assembly peptide is proposed to construct nanofibrous barriers on the cell membrane in situ, which contributes to...
In article number 2004548, Lei Wang, Ziqi Wang, Hao Wang, Wanhai Xu, and co‐workers propose a transformable dual‐inhibition system (TDS) based on a self‐assembly peptide to reduce metastasis of renal cancer via the inhibition of neovascular endothelial cells and cancer stem cells simultaneously. The TDS has great value in suppressing renal cancer metastasis. Additionally, this newly developed TDS...
Large‐area flexible pressure sensors are of paramount importance for various future applications, such as electronic skin, human–machine interfacing, and health‐monitoring devices. Here, a self‐powered and large‐area integrated triboelectric sensor array (ITSA) based on coupling a triboelectric sensor array and an array chip of CD4066 through a traditional connection is reported. Enabled by a simple...
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