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An assay for protein dimers using surface‐enhanced Raman scattering (SERS) is presented, in article number 1700802, by Sebastian Schlücker and co‐workers. Site‐specific binding of the Survivin protein dimer to molecularly functionalized gold nanoparticles results in the formation of protein‐bridged dimers of gold nanoparticles. The dimers exhibit the characteristic SERS spectrum of Raman reporter...
An assay for Survivin, a small dimeric protein which functions as modulator of apoptosis and cell division and serves as a promising diagnostic biomarker for different types of cancer, is presented. The assay is based on switching on surface‐enhanced Raman scattering (SERS) upon incubation of the Survivin protein dimer with Raman reporter‐labeled gold nanoparticles (AuNP). Site‐specificity is achieved...
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