Search results for: K. Laskowska

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article

Evaluation of keratin biomaterial containing silver nanoparticles as a potential wound dressing in full‐thickness skin wound model in diabetic mice

Marek Konop, Joanna Czuwara, Ewa Kłodzińska, Anna K. Laskowska, more

Journal of Tissue Engineering and Regenerative Medicine > 14 > 2 > 334 - 346

Keratin is a cytoskeletal scaffolding protein essential for wound healing and tissue recovery. The aim of the study was to evaluate the potential role of insoluble fur keratin‐derived powder containing silver nanoparticles (FKDP‐AgNP) in the allogenic full‐thickness surgical skin wound model in diabetic mice. The scanning electron microscopy image evidenced that the keratin surface is covered by a...

article

Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1

Karolina Grabowska, Anna K. Puszko, Piotr F.J. Lipiński, Anna K. Laskowska, more

Bioorganic & Medicinal Chemistry > 2017 > 25 > 2 > 597-602

Inhibition of angiogenesis is one of the most promising approaches in anticancer therapy. It was recently suggested that Neuropilin-1 (NRP-1) in tumour cells may serve as a separate receptor for Vascular Endothelial Growth Factor-165 (VEGF₁₆₅) which is one of the main pro-angiogenic agents in the organism. Therefore molecules inhibiting VEGF₁₆₅ binding to NRP-1 could be potential candidates for new...

article

BDNF expression in cat striate cortex is regulated by binocular pattern deprivation

K. Laskowska-Macios, L. Arckens, M. Kossut, K. Burnat

Acta Neurobiologiae Experimentalis > 2017 > 77 > 3

Deprivation of patterned visual information, as in early onset congenital cataract patients, results in a severe impairment in global motion perception. Previously we reported a delayed maturation of the peripheral visual field representation in primary visual area 17, based on a 2‑D DIGE screen for protein expression changes and in situ hybridization for the activity reporter gene ZIF268. To corroborate...

article

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

Karolina Grabowska, Anna K. Puszko, Piotr F.J. Lipiński, Anna K. Laskowska, more

Bioorganic & Medicinal Chemistry Letters > 2016 > 26 > 12 > 2843-2846

Neuropilin-1 (NRP-1) is a co-receptor of VEGFR (vascular endothelial growth factor receptor), but it is also suggested that NRP-1 in tumour cells may serve as a separate receptor for VEGF₁₆₅. Therefore molecules interfering with VEGF₁₆₅ binding to NRP-1 seem to be promising candidates as new anti-angiogenic and anti-tumour drugs. Here, we report the design, synthesis, biological evaluation and molecular...

article

Pożary lasów - sposoby prognozowania i zapobiegania

A. Ubowska, K. Laskowska

Aura > 2016 > 1

article

Early onset binocular pattern deprivation differentiates developmental gene and protein expression changes between central and peripheral visual field representation in cat area 17

K. Laskowska-Macios, T.-T. Hu, M. Kossut, K. Burnat, more

International Journal of Developmental Neuroscience > 2015 > 47 > Part A > 50

article

Beyond amyloid:altered cell cycle regulation in Alzheimer's disease:comparison of P21 signaling in patients lymphocytes and brain neurons

A. Mietelska-Porowska, J. Wojsiat, K. Laskowska-Kaszub, T. Stepien, more

Acta Neurobiologiae Experimentalis > 2015 > 75 > Supl.

BACKGROUND AND AIMS: Alzheimer’s disease (AD) develops for decades, but the molecular mechanism of pathogenesis is poorly understood. In result, an effective AD cure is still missing. According to the cell cycle (CC) hypothesis, one of the AD causes is CC reactivation in mature neurons. We aimed at elucidation if similar CC alterations occur in AD brain neurons and in peripheral blood cells. METHODS:...

article

Alterations in apoptotic signaling in lymphocytes of patients in early stage of Alzheimer's disease precede massive neuronal loss in the brain

J. Wojsiat, K. Laskowska-Kaszub, M. Mandecka, T. Gabryelewicz, more

Acta Neurobiologiae Experimentalis > 2015 > 75 > Supl.

BACKGROUND AND AIMS: Alzheimer’s disease (AD) is the most common age-related dementia worldwide of unclear early pathogenesis. Mild Cognitive Impairment (MCI) represents an early AD stage, preceding massive deposition of Aβ aggregates and associated neuronal loss in the brain. Recently we demonstrated that sporadic AD (SAD) lymphoblasts show increased levels of p21 protein, the key regulator of G1/S...

article

PP135. Maternal serum levels of endothelial nitric oxide synthase and ADMA, an endogenous ENOS inhibitor in pregnancies complicated by severe preeclampsia

M. Laskowska, K. Laskowska, J. Oleszczuk

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2012 > 2 > 3 > 312

Preeclampsia is a major cause of maternal and fetal mortality and morbidity. Preeclampsia remains amongst the biggest challenges in obstetrics, but its aetiopathogenesis is still unclear. Recent observations support the hypothesis that imbalance between maternal angiogenic/anti-angiogenic factors concentrations is responsible for the clinical manifestations of the preeclampsia. It was also suggested...

article

Binocular deprivation reveals early plasticity-dependent region- and layer- specific zif268 expression profiles in cat primary visual cortex (area 17)

K. Laskowska-Macios, M. Zapasnik, T.T. Hu, M. Kossut, more

Acta Neurobiologiae Experimentalis > 2011 > 71 > S

Rekord w opracowaniu

article

Effects of pattern deprivation on the development of the motion-sensitive posterior medial lateral suprasylvian (PMLS) visual area of the cat as revealed by zif268 gene expression

M. Zapasnik, K. Laskowska-Macios, T.T. Hu, M. Kossut, more

Acta Neurobiologiae Experimentalis > 2011 > 71 > S

Rekord w opracowaniu

article

Moulded plywood elements for furniture made of thermally modified beech veneers

M. Grzeskiewicz, K. Laskowska

Annals of Warsaw University of Life Sciences - SGGW. Forestry and Wood... > 2010 > 70

Moulded plywood elements for furniture made of thermally modified beech veneers. This paper presents test results for thermally-modified veneers in laboratory conditions used as raw materials for manufacture of laminate bended elements in industrial conditions. Moulded plywood elements were made of rotary-cut beech veneers. Veneers were thermally modified in laboratory conditions (190°C; 0,5 and 1,5...

article

Evolution of the Organized Crime in Russia

K. Laskowska

Miscellanea Historico-Iuridica > 2008 > 6 > 55-66

The article presents the development of the organized crime in Russia. The authoress has identified four stages of the evolution: period before the Bolshevik Revolution in 1917, then years 1917-1945, years 1945-1991 and finally period starting from 1991. She presents an opinion that the political events in each of these periods had big influence on shape of this kind of crime. The important role is...

article

REACTION IN THE AREA OF PENAL LAW ON ESTABLISHING, PARTICIPATING AND LEADING OF CRIMINAL GROUP IN THE UKRAINIAN PENAL CODE

K. Laskowska

Studia Prawnicze > 2007 > 2(172) > 123-133

Organized crime in Ukraine presently constitutes a serious problem, which requires a reaction of the government in the area of penal law. Consequently, the Ukrainian Penal Code of 2001 includes (along a number of other regulations) a provision that penalizes establishing, participating in, and leading a criminal organization (Art. 255 of PC). In order to better explain this provision, first the terms...

article

CRIMINOLOGICAL ASPECTS OF BORDER CRIME

K. Laskowska

Archiwum Kryminologii > 2004 > 26 > 161-180

The authoress indicates the main problems that appeared in Poland as a result of the opening of borders after the 1989 transition to a new economic and political system. Border crime, being one of them, is defined here as both illegal border crossing, customs and currency offenses, forgery of documents and crime against institutions. Among the internal grounds contributing to its growth, the closure...

article

Angiotensin-converting enzyme activity in pre-eclampsia

M. Laskowska, K. Laskowska, J. Oleszczuk

International Journal of Gynecology and Obstetrics > 2002 > 77 > 1 > 33-34

article

Serotonin in pre-eclampsia

M. Laskowska, K. Laskowska, J. Oleszczuk

International Journal of Gynecology and Obstetrics > 2001 > 75 > 1 > 83-84

article

Zabezpieczenie płatności: ubezpieczenie

K. Laskowska

Gospodarka Materiałowa i Logistyka > 2001 > nr 3 > 22-23

article

Factoring jako sposób zabezpieczenie płatności

K. Laskowska

Gospodarka Materiałowa i Logistyka > 2001 > nr 1 > 24-25

article

Zabezpieczenia płatności: forfaiting

K. Laskowska

Gospodarka Materiałowa i Logistyka > 2001 > nr 8 > 26-27

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INFONA - science communication portal

Search results for: K. Laskowska

Evaluation of keratin biomaterial containing silver nanoparticles as a potential wound dressing in full‐thickness skin wound model in diabetic mice

Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1

BDNF expression in cat striate cortex is regulated by binocular pattern deprivation

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

Pożary lasów - sposoby prognozowania i zapobiegania

Early onset binocular pattern deprivation differentiates developmental gene and protein expression changes between central and peripheral visual field representation in cat area 17

Beyond amyloid:altered cell cycle regulation in Alzheimer's disease:comparison of P21 signaling in patients lymphocytes and brain neurons

Alterations in apoptotic signaling in lymphocytes of patients in early stage of Alzheimer's disease precede massive neuronal loss in the brain

PP135. Maternal serum levels of endothelial nitric oxide synthase and ADMA, an endogenous ENOS inhibitor in pregnancies complicated by severe preeclampsia

Binocular deprivation reveals early plasticity-dependent region- and layer- specific zif268 expression profiles in cat primary visual cortex (area 17)

Effects of pattern deprivation on the development of the motion-sensitive posterior medial lateral suprasylvian (PMLS) visual area of the cat as revealed by zif268 gene expression

Moulded plywood elements for furniture made of thermally modified beech veneers

Evolution of the Organized Crime in Russia

REACTION IN THE AREA OF PENAL LAW ON ESTABLISHING, PARTICIPATING AND LEADING OF CRIMINAL GROUP IN THE UKRAINIAN PENAL CODE

CRIMINOLOGICAL ASPECTS OF BORDER CRIME

Angiotensin-converting enzyme activity in pre-eclampsia

Serotonin in pre-eclampsia

Zabezpieczenie płatności: ubezpieczenie

Factoring jako sposób zabezpieczenie płatności

Zabezpieczenia płatności: forfaiting

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