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We investigated the genotype frequency of methylenetetrahydrofolate reductase (MTHFR) 1298A>C polymorphism in the group of patients with bipolar disorder type I (BDI) (n=200) and schizophrenia (n=200) and in the control group (n=300). Odds ratio (OR) for patients with BD and schizophrenia in 1298CC homozygous state was 3.768 (95% CI=1.752–8.104); P=0.0003; (P=0.0006 after Bonferroni correction)...
A polymorphism of serotonin transporter was studied in 226 patients with affective disorders (n = 132 for bipolar, n = 94 for unipolar affective disorder) and in 213 healthy subjects. Consensus diagnosis by at least two psychiatrists, according to the ICD-10 and DSM-IV criteria was made for each patient using SCID (Structured Clinical Interview for DSM-IV Axis I Disorders). A functional polymorphism...
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