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Background Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are forms of hepatic autoimmunity, and risk for both diseases has a strong genetic component. This study aimed to define the genetic architecture of PBC and PSC within the Polish population. Methods Subjects were 443 women with PBC, 120 patients with PSC, and 934 healthy controls recruited from Gastroenterology...
Background & AimsPrimary biliary cirrhosis and Primary sclerosing cholangitis are autoimmune cholestatic liver diseases sharing a lot in common, including a significant impairment of patients’ health‐related quality of life HRQoL HRQoL in PBC is assessed with disease‐specific PBC‐40 and PBC‐27 questionnaires. A PSC‐specific questionnaire has not been developed. Neither PBC‐40 nor PBC‐27s applicability...
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