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Green solvents

Collection editor: Maciej Przybyłek
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Editors

Maciej Przybyłek

Fields of science

Chemical Engineering, Materials Engineering and 1 other see all

Elements

article

New Screening Protocol for Effective Green Solvents Selection of Benzamide, Salicylamide and Ethenzamide

Maciej Przybyłek, Anna Miernicka, Mateusz Nowak, Piotr Cysewski

New protocol for screening efficient and environmentally friendly solvents was proposed and experimentally verified. The guidance for solvent selection comes from computed solubility via COSMO-RS approach. Furthermore, solute-solvent affinities computed using advanced quantum chemistry level were used as a rationale for observed solvents ranking. The screening protocol pointed out that 4-formylomorpholine...
article

Experimental and Theoretical Screening for Green Solvents Improving Sulfamethizole Solubility

Piotr Cysewski, Maciej Przybyłek, Rafal Rozalski

Solubility enhancement of poorly soluble active pharmaceutical ingredients is of crucial importance for drug development and processing. Extensive experimental screening is limited due to the vast number of potential solvent combinations. Hence, theoretical models can offer valuable hints for guiding experiments aimed at providing solubility data. In this paper, we explore the possibility of applying...
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