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A solid lipid nanoparticle (SLN) formulation for intravenous injection was developed as drug carrier for potential human use. The lipid matrix was composed of glycerolbehenate (compritol), the dispersions stabilized by poloxamer 188 - a surfactant accepted for intravenous administration. The in vitro uptake of SLN by human granulocytes was determined by chemiluminescence (CL), cytotoxicity was assessed...
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