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Myocardial strain imaging has been shown to add significant prognostic and diagnostic value to echocardiography. While the reliability of ultrasound-based strain measurement techniques has improved considerably in terms of regional consistency and inter-reader, inter-vendor agreement; most state-of-the-art strain imaging packages constrain their analyses to individual cardiac cycles. This limitation...
Ultrasound elastography is an effective modality for the delineation of thermally ablated regions after liver tumor treatments. Image contrast in elasticity imaging is based on differences in the Young's modulus of local tissue. In this work, we compare our previously introduced electrode displacement elastography (EDE) with a commercially available acoustic radiation force impulse imaging (ARFI)...
Ultrasound based carotid strain imaging (CSI) developed in our laboratory utilizes physiological deformation in response to arterial pressure variations. We have shown that strain indices are capable of quantifying vulnerability of carotid plaque, enhancing their validity as vascular biomarkers. However, a critique of CSI has been the lack of normalization of the maximum and peak-to-trough strain...
Fast acquisition sequences enable >200Hz 2D cardiac B-mode imaging with little compromise in image quality. Fast imaging minimizes frame to frame decorrelation, enabling RF-based tracking for enhanced signal-to-noise ratio (SNR) in motion and deformation imaging. Our objective was to evaluate the performance and hypothesize on the clinical usefulness of Fast RF-based Tracking (FRFT) in comparison...
Carotid plaque rupture is a primary cause of ischemic strokes and transient ischemic attacks (TIAs). Probability of stroke and TIAs depend on the mechanical stability of plaque. Ultrasound strain can provide a non-invasive assessment of plaque stiffness to assess mechanical stability. We report on ultrasound strain indices from multiple regions of interest (ROI) in plaque as biomarkers for plaque...
Atherosclerosis in the carotid artery (CA) elevates the risk for cerebral events. Strain imaging has demonstrated to be a technique capable of identifying plaque composition. For strain imaging of carotid cross-sections, compound techniques have been developed to solve the poor strain estimation quality perpendicular to the ultrasound beam direction. This study assesses the performance of radial and...
In last decade, composite materials have been used widely in industrial area. Structural elements produced from the composites possess more complicate mechanical properties than components manufactured from isotropic materials. Therefore, imaging algorithms of defects in anisotropic materials have not yet been developed well, because of anisotropic properties of elastic media affect much on the shape...
Because conventional geophysical measurements cannot directly measure the microstructure or pore fluids of rocks, new measurement approaches are needed as well as one that can select regions of interest. The aim of this study is to utilize the nonlinear interaction of two co-propagating longitudinal waves to characterize induced viscoelastic changes occurring in the rock microstructure. Our experimental...
Fast acquisition sequences enable >200Hz 2D cardiac B-mode imaging with little compromise in image quality. Fast imaging minimizes frame to frame decorrelation, enabling radiofrequency (RF)-based tracking for enhanced signal-to-noise ratio (SNR) in motion and deformation imaging. Our objective was to compare the performance and clinical usefulness of Fast RF-based Tracking (FRFT) to the established...
Ultrasound is a widely used imaging modality, both for diagnosis and guidance of interventional procedures such as biopsies. Ultrasound imaging commonly provides 2D data, which can be a limitation for further data processing, since information like out-of-plane motion is inaccessible. In this study, a specific multi-row array transducer — developed for the elastography application — is presented....
An effective imaging modality to delineate ablated regions after microwave ablation (MWA) therapy is crucial to yield successful treatment outcomes. Ultrasound B-mode imaging is widely used to guide the ablation antenna placement. However, the image quality suffers from relatively low imaging contrast due to the similar echogenicity between the ablated and surrounding tissue. In this study, we applied...
Tissue Doppler Imaging (TDI) is an excellent tool for early detection of myocardial dysfunction, as well as for prognosis and follow-up of myocardial function after surgical treatment. However, since it exploits the same principles of color flow imaging, TDI requires to balance frame rate with field of view. A novel TDI technique, based on multi-line transmission and multi-line acquisition, was shown...
Assessing the response of heart failure (HF) patients to Cardiac Resynchronization Therapy (CRT) currently relies on the ECG and left ventricular (LV) ejection fraction. Electromechanical Wave Imaging (EWI) is a high frame-rate (2000 Hz) ultrasound-based technique capable of non-invasively mapping the electromechanical activation in all four cardiac chambers in vivo. In this study, we aim to show...
An effective imaging modality to delineate the ablated region after microwave ablation (MWA) therapy is crucial to yield promising treatment outcomes. Ultrasound B mode imaging is widely used to guide the ablation needle. However, the image quality suffers from relatively low imaging contrast due to the similar echogenicity between the ablated and surrounding liver tissue. In this study, we applied...
Speckle tracking echocardiography (STE) is a very promising technique for the assessment of left ventricular (LV) function. Nevertheless, to date, it did not become part of clinical routine due to: i) inter-vendor variability; ii) difficulties in data interpretation. Anthropomorphic patient characteristics (APC) are known to affect the LV strain values as studies have shown the effect of gender, age,...
Individuals infected with the human immunodeficiency virus (HIV) are prone to develop cardiovascular disease (CVD) because the HIV infection and combination antiretroviral therapy (cART) produces atherosclerosis. Clinicians need sensitive tests to monitor interventions designed to prevent CVD in patients with HIV on long term cART. We hypothesize that vascular elastography can fulfill this role. To...
Strain imaging is gaining traction as a means to assess cardiac function by tracking the cyclic deformation of the myocardium. Compared to traditional measures such as ejection fraction, global myocardial strain has been shown to be an earlier and more sensitive measure of overall ventricular function. Similarly, regional myocardial strain has been shown to be useful for identifying ischemia and myocardial...
Myocardial elastance, derived from pressure-volume (PV) loops in the left ventricle (LV), can be used to assess LV function and myocardial performance. This method requires an invasive intracardiac pressure-volume catheter to be inserted in the LV, limiting the method's utility in clinical screening and monitoring. Strain echocardiography and cardiac acoustic radiation force impulse (ARFI) imaging...
Current elastography techniques can measure mechanical properties of soft tissues by estimating the elastic shear modulus, μ0. Recently, the assessment of tissue nonlinearity using acoustoelasticity (AE) has shown some promising results in differentiating healthy from malignant tissue by estimating a third-order nonlinear coefficient A. To fully characterize the nonlinear properties of the tissue,...
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