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Increasing evidence points to a close relationship between the autonomic nervous system and the immune system. To further investigate mechanisms regulating β 2 -adrenergic receptor (β 2 R) expression in lymphocytes, the influence of cytokines on the density of β 2 R on purified CD4 + and CD8 + lymphocytes was determined in vitro. β 2 R were determined...
Previous investigations have demonstrated a decrease of the number of β 2 -adrenergic receptors (β2R) on peripheral blood mononuclear cells (PBMC) in patients with rheumatic diseases that correlated with systemic inflammatory activity. However, the main factor(s) modulating the β2R on lymphocytes in inflammatory diseases are still unidentified. The present study aimed at evaluating the influence...
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